Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide

RA Heiser, CM Snyder, J St Clair… - The Journal of …, 2011 - journals.aai.org
A fundamental problem in immunoregulation is how CD4+ T cells react to immunogenic
peptides derived from the V region of the BCR that are created by somatic mechanisms …

Novel nicotine DNA vaccines

Y Chang, H Yan, S Hecht, P Pentel, X Liu… - US Patent App. 14 …, 2015 - Google Patents
(21) Appl. No.: 14/209,845 i and at least one Erin moiety, wherein the at least (22) Filed: Mar
13, 2014 one targeting moiety is linked to the DNA-nanostructure; and Related US …

The generation of influenza-specific humoral responses is impaired in ST6Gal I-deficient mice

J Zeng, HM Joo, B Rajini, JP Wrammert… - The Journal of …, 2009 - journals.aai.org
Posttranslational modification of proteins, such as glycosylation, can impact cell signaling
and function. ST6Gal I, a glycosyltransferase expressed by B cells, catalyzes the addition of …

滤泡辅助性T 细胞的研究进展

刘巍 - 国际免疫学杂志, 2010 - cqvip.com
滤泡辅助性T 细胞(Tfh) 是最近发现的CD4^+ 辅助性T 淋巴细胞亚群, 其作用是辅助B
细胞的抗体产生. 其发生, 分化和功能均独立于以往的Th1, Th2 和Th17 细胞 …

Immunophenotyping in multiple myeloma and others monoclonal gammopathies

L Rihova, KRM Raja, LAC Leite… - Multiple Myeloma—A …, 2013 - books.google.com
Clonal plasma cell disorders (PCD) including mostly monoclonal gammopathy of undeter‐-
mined significance (MGUS) and multiple myeloma (MM) are characterised by expansion of …

Bcl-6/Blimp-1/IL-21 在原发性干燥综合征中的致病作用

段春巧, 杨雯雯, 雷玲彦, 郭惠芳, 张明峰, 高丽霞… - 中国免疫学杂志, 2015 - cqvip.com
目的: 分析Bcl-6/Blimp-1/IL-21 在原发性干燥综合征发病机制中的作用, Bcl-6/Blimp-1/IL-21
的表达与唇腺活检病理分级的关系; 方法: 应用免疫组织化学法检测Bcl-6/Blimp-1 在疾病组30 …

Analysis of B-cell subpopulations in monoclonal gammopathies

P Všianská, L Říhová, T Varmužová, R Suská… - … Myeloma and Leukemia, 2015 - Elsevier
Background Multiple myeloma (MM) is characterized by accumulation of pathological
plasma cells (PCs) in bone marrow (BM) as a result of deregulation of B-cell development …

Random walks on binary strings applied to the somatic hypermutation of B-cells

I Balelli, V Milišić, G Wainrib - Mathematical biosciences, 2018 - Elsevier
Within the germinal center in follicles, B-cells proliferate, mutate and differentiate, while
being submitted to a powerful selection: a micro-evolutionary mechanism at the heart of …

[HTML][HTML] Increased p190RhoGEF expression in activated B cells correlates with the induction of the plasma cell differentiation

YJ Ha, JH Jeong, Y Park, JR Lee - Experimental & Molecular Medicine, 2012 - nature.com
Previously, we demonstrated that the p190 Rho guanine nucleotide exchange factor
(p190RhoGEF) was induced following CD40 stimulation of B cells. In this study, we …

[HTML][HTML] Paternal kinship among adult female rhesus macaques (Macaca mulatta)

A Widdig - 2003 - edoc.hu-berlin.de
Adel und Militär in Ost- und Westpreußen zum Ende des 18. Jahrhunderts Page 1 Adel und
Militär in Ost- und Westpreußen zum Ende des 18. Jahrhunderts Di sserta tio n zur …