Genetic mutations frequently observed in human follicular lymphoma (FL) B-cells result in
aberrant expression of the anti-apoptotic protein bcl-2 and surface immunoglobulins (Igs) …

Antigen-specific recognition and memory, the hallmarks of conventional mammalian
adaptive immunity, are found in all jawed vertebrates along with all elements central to …

Many cellular systems exist in more than one state. Two of the simplest and best-
characterized examples are bacteriophage A, which can be in the lytic or lysogenic state …

Em 1968, Mitchell & Miller() publicaram um artigo que demonstrou pela primeira vez as
células T do timo interagindo com as células B da medula óssea para produção de …

B cells have both positive and negative regulatory roles during immune responses; they
have role in the pathogenesis of various neuroimmunological diseases such as Myasthenia …

B and T lymphocytes activate the humoral and cellular arms of the adaptive immune system.
The adaptive strategy works because receptors of adaptive immune cells can mount an …

Vaccination has emerged as one of the cheapest and most important healthcare
interventions, saving millions of lives in both developed and developing countries. Currently …

The most critical issue for the application of high affinity monoclonal antibodies is their
creation. Here, we summarize the cellular and molecular mechanisms by which high affinity …

Langlebige Gedächtnisplasmazellen sind die Quelle persistierender Antikörper. Nach einer
Infektion oder Impfung ist ein protektiver Antikörpertiter über Jahre bis Jahrzehnte im Serum …

The lymphadenoid tissues in the upper airway are relatively organized lymphoepithelial
structures that play an important role in protecting the upper airway against foreign …