[HTML][HTML] Nanoemulsions for drug delivery
Emulsions are liquid–liquid dispersions with one liquid phase dispersed in the other liquid
phase as small droplets. Nanoemulsions are nano-sized emulsions with sizes ranging from …
phase as small droplets. Nanoemulsions are nano-sized emulsions with sizes ranging from …
Aging and lung disease
SJ Cho, HW Stout-Delgado - Annual review of physiology, 2020 - annualreviews.org
People worldwide are living longer, and it is estimated that by 2050, the proportion of the
world's population over 60 years of age will nearly double. Natural lung aging is associated …
world's population over 60 years of age will nearly double. Natural lung aging is associated …
Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples
The COVID-19 pandemic has emerged as a global health emergency due to its association
with severe pneumonia and relative high mortality. However, the molecular characteristics …
with severe pneumonia and relative high mortality. However, the molecular characteristics …
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
MSD Kormann, G Hasenpusch, MK Aneja, G Nica… - Nature …, 2011 - nature.com
Current viral vectors for gene therapy,, are associated with serious safety concerns,
including leukemogenesis, and nonviral vectors are limited by low gene transfer efficiency …
including leukemogenesis, and nonviral vectors are limited by low gene transfer efficiency …
Physicochemical properties affecting the fate of nanoparticles in pulmonary drug delivery
Q Liu, J Guan, L Qin, X Zhang, S Mao - Drug discovery today, 2020 - Elsevier
Highlights•Clearance routes of nanoparticles in the lung are presented.•Factors influencing
nanoparticle transaction are discussed.•Physicochemical properties of the nanoparticles …
nanoparticle transaction are discussed.•Physicochemical properties of the nanoparticles …
Pulmonary alveolar proteinosis
BC Trapnell, JA Whitsett, K Nakata - New England Journal of …, 2003 - Mass Medical Soc
In acquired pulmonary alveolar proteinosis, lipids and proteins accumulate within the alveoli
because alveolar macrophages cannot catabolize surfactants. Surprisingly, alveolar …
because alveolar macrophages cannot catabolize surfactants. Surprisingly, alveolar …
[HTML][HTML] Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy
E Lopez-Rodriguez, J Pérez-Gil - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Pulmonary surfactant is an essential lipid–protein complex to maintain an operative
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
Pulmonary surfactant: A mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease
JA Whitsett, SE Wert, TE Weaver - Annual review of medicine, 2010 - annualreviews.org
The alveolar region of the lung creates an extensive epithelial surface that mediates the
transfer of oxygen and carbon dioxide required for respiration after birth. Maintenance of …
transfer of oxygen and carbon dioxide required for respiration after birth. Maintenance of …
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection
WE Lawson, PF Crossno… - … of Physiology-Lung …, 2008 - journals.physiology.org
Recent evidence suggests that dysfunctional type II alveolar epithelial cells (AECs)
contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Based on the …
contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Based on the …