Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

Rationale: Coronavirus disease (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). ACE2 (angiotensin-converting enzyme 2), and …

Hypertension is a common and complex human disease that causes significant morbidity
and mortality worldwide. Unfortunately, despite recent advances in understanding and …

В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

A population‐based study of a quantitative trait may be seriously compromised when the
trait is subject to the effects of a treatment. For example, in a typical study of quantitative …

The renin-angiotensin-aldosterone system (RAAS) is a specific hormonal cascade
implicated in the blood pressure control and sodium balance regulation. Several …

Type 2 diabetes mellitus (T2DM) is a global public health problem of epidemic proportions,
with 60–70% of affected individuals suffering from associated neurovascular complications …

Hypertension, characterised by a constant high blood pressure, is the primary risk factor for
multiple cardiovascular events and a major cause of death in adults. Excitingly, innovations …

Hypertension is a multifactorial disorder that probably results from the inheritance of a
number of susceptibility genes and involves multiple environmental determinants. Existing …

The aim of the present study was to investigate whether methylation of the angiotensin I
converting enzyme 2 (ACE2) promoter increases the risk of essential hypertension (EH). A …