Care for patients with acute respiratory distress syndrome (ARDS) has changed
considerably over the 50 years since its original description. Indeed, standards of care …

Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an
emerging viral pathogen that causes the novel coronavirus disease of 2019 (COVID-19) and …

Acute respiratory distress syndrome (ARDS) is a clinically and biologically heterogeneous
disorder associated with a variety of disease processes that lead to acute lung injury with …

Mortality related to severe-moderate and severe ARDS remains high. We searched the
literature to update this topic. We defined severe hypoxemic respiratory failure as Pa o 2/F io …

Background It is uncertain whether airway pressure release ventilation (APRV) is better than
low tidal volume ventilation (LTVV) for patients with acute respiratory distress syndrome …

Objective: To review the theoretical benefits of airway pressure release ventilation (APRV),
summarize the evidence for its use in clinical practice, and discuss different titration …

In the pursuit of science, competitive ideas and debate are necessary means to attain
knowledge and expose our ignorance. To quote Murray Gell-Mann (1969 Nobel Prize …

Objectives: Low tidal volume (= tidal volume≤ 6 mL/kg, predicted body weight) ventilation
using volume control benefits patients with acute respiratory distress syndrome. Airway …

Background: Obstructive sleep apnea hypopnea syndrome (OSAHS) is defined as more
than 30 recurrent episodes of apnea or a sleep apnea hypopnea index (AHI) of more than 5 …

Airway pressure release ventilation (APRV) is a ventilator mode that has previously been
considered a rescue mode, but has gained acceptance as a primary mode of ventilation. In …