Open microfluidics: droplet microarrays as next generation multiwell plates for high throughput screening

R Strutt, B Xiong, VF Abegg, PS Dittrich - Lab on a Chip, 2024 - pubs.rsc.org
Multiwell plates are prominent in the biological and chemical sciences; however, they face
limitations in terms of throughput and deployment in emerging bioengineering fields. Droplet …

Metabolism-Triggered Plasmonic Nanosensor for Bacterial Detection and Antimicrobial Susceptibility Testing of Clinical Isolates

J Zhang, M Wang, J Xiao, M Wang, Y Liu, X Gao - ACS sensors, 2024 - ACS Publications
Antimicrobial resistance (AMR) is predicted to become the leading cause of death worldwide
in the coming decades. Rapid and on-site antibiotic susceptibility testing (AST) is crucial for …

[HTML][HTML] Advances in AI-assisted biochip technology for biomedicine

DR Solovchuk - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The integration of biochips with AI opened up new possibilities and is expected to
revolutionize smart healthcare tools within the next five years. The combination of …

Simultaneous Separating, Splitting, Collecting, and Dispensing by Droplet Pinch‐Off for Droplet Cell Culture

SJ Bae, SJ Lee, DJ Im - Small, 2024 - Wiley Online Library
Simultaneous separating, splitting, collecting, and dispensing a cell suspension droplet has
been demonstrated by aspiration and subsequent droplet pinch‐off for use in microfluidic …

Microfluidic technologies for advanced antimicrobial susceptibility testing

W Wu, Y Mu - Biomicrofluidics, 2024 - pubs.aip.org
Antimicrobial resistance is getting serious and becoming a threat to public health worldwide.
The improper and excessive use of antibiotics is responsible for this situation. The standard …

In vitro neutrophil functional assay in microliter whole blood for days-long extraction of donor-specific information

C Li, NW Hendrikse, M Mai, Z Argall-Knapp, JS Kim… - medRxiv, 2023 - medrxiv.org
For in vitro neutrophil functional assays, isolated neutrophils are typically used as the
standard input. However, isolated neutrophils show a varying and limited lifespan as short …

Combining Top-Down and Bottom-Up: An Open Microfluidic Microtumor Model for Investigating Tumor Cell-ECM Interaction and Anti-Metastasis

C Li, J Li, Z Argall-Knapp, NW Hendrikse, MA Farooqui… - bioRxiv, 2024 - biorxiv.org
Using a combined top-down (ie, operator-directed) and bottom-up (ie, cell-directed) strategy,
we present an Under-oil Open Microfluidic System (UOMS)-based microtumor model for …