[HTML][HTML] Biomaterials for Testicular Bioengineering: How far have we come and where do we have to go?

BO Horvath-Pereira, GHDR Almeida… - Frontiers in …, 2023 - frontiersin.org
Traditional therapeutic interventions aim to restore male fertile potential or preserve sperm
viability in severe cases, such as semen cryopreservation, testicular tissue, germ cell …

[HTML][HTML] Novel aspects of cAMP-response element modulator (CREM) role in spermatogenesis and male fertility

DE Sánchez-Jasso, SF López-Guzmán… - International Journal of …, 2023 - mdpi.com
Spermatogenesis is a very complex process with an intricate transcriptional regulation. The
transition from the diploid to the haploid state requires the involvement of specialized genes …

[HTML][HTML] Minipuberty in Sons of Women with Low Vitamin D Status during Pregnancy

K Kowalcze, R Krysiak, A Obuchowicz - Nutrients, 2023 - mdpi.com
Minipuberty is a transient phase of reproductive axis activation during the first several
months of life, playing an important role in the development of reproductive organs in boys …

Using Selenium-enriched Mutated Probiotics as Enhancer for Fertility Parameters in Mice

AM Darwish, AA Almehiza, AEN Khattab… - Biological trace element …, 2024 - Springer
Increasing fertility rates have become one of the factors that concern all people in the world.
Therefore, the study aims to use two mutated strains of probiotics enriched with selenium …

Regulation of Cdh2 by the AP-1 family transcription factor Junb in TM4 Sertoli cells

HT Nguyen, LJ Martin - Biochemical and Biophysical Research …, 2023 - Elsevier
Cadherins are transmembrane proteins that mediate cell-to-cell adhesion and various
cellular processes. In Sertoli cells of the testis, Cdh2 contributes to the development of the …

[HTML][HTML] LanCL2 Implicates in Testicular Redox Homeostasis and Acrosomal Maturation

Y Zhao, J Wang, S Shi, X Lan, X Cheng, L Li, Y Zou… - Antioxidants, 2024 - mdpi.com
Redox balance plays an important role in testicular homeostasis. While lots of antioxidant
molecules have been identified as widely expressed, the understanding of the critical …

Investigational follicle-stimulating hormone receptor agonists for male infertility therapy

R Cannarella, CMB Petralia, RA Condorelli… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction According to estimates by the World Health Organization, about 17.5% of the
adult population–roughly 1 in 6 globally–experience infertility. The causes of male infertility …

[HTML][HTML] ATP10A deficiency results in male-specific infertility in mice

AC Norris, EM Yazlovitskaya, TS Yang… - Frontiers in Cell and …, 2024 - ncbi.nlm.nih.gov
Over 8% of couples worldwide are affected by infertility and nearly half of these cases are
due to male-specific issues where the underlying cause is often unknown. Therefore …

[HTML][HTML] FSH promotes immature porcine Sertoli cell proliferation by activating the CCR7/Ras-ERK signaling axis

Y Yin, J Ma, X Lu, S Yan, Q Jiang, D Wu… - …, 2023 - rep.bioscientifica.com
In brief The appropriate growth and functions of Sertoli cells are crucial to testis development
and spermatogenesis in mammals. This study reveals a novel mechanism of follicle …

[HTML][HTML] Hormone Regulation in Testicular Development and Function

L Li, W Lin, Z Wang, R Huang, H Xia, Z Li… - International Journal of …, 2024 - mdpi.com
The testes serve as the primary source of androgens and the site of spermatogenesis, with
their development and function governed by hormonal actions via endocrine and paracrine …