Diffuse reflectance spectroscopy, which has been demonstrated as a noninvasive diagnostic
technique, relies on quantitative models for extracting optical property values from turbid …

We present a method for tissue fluorescence quantification in situ using a handheld fiber
optic probe that measures both the fluorescence and diffuse reflectance spectra. A simplified …

Biomarkers are indicators of biological processes and hold promise for the diagnosis and
treatment of disease. Gliomas represent a heterogeneous group of brain tumors with marked …

BACKGROUND: The use of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX)
fluorescence has shown promise as a surgical adjunct for maximizing the extent of surgical …

Fluorescence guided surgery (FGS) using aminolevulinic-acid (ALA) induced protoporphyrin
IX (PpIX) provides intraoperative visual contrast between normal and malignant tissue …

Light Scattering Technology for Food Property, Quality and Safety Assessment discusses the
development and application of various light scattering techniques for measuring the …

Melanoma is the most aggressive type of skin cancer, with significant risk of fatality. Due to
its pigmentation, light-based imaging and treatment techniques are limited to near the tumor …

Background Malignant gliomas are highly invasive, difficult to treat, and account for 2% of
cancer deaths worldwide. Glioblastoma Multiforme (GBM) comprises the most common and …

The feasibility of spatial frequency domain imaging (SFDI) for breast surgical margin
assessment was evaluated in tissue-simulating phantoms and in fully intact lumpectomy …

This paper presents a relationship between the intensity collected by a single fiber
reflectance device (RSF) and the fiber diameter (dfib) and the reduced scattering coefficient …