Small interfering RNAs in the management of human osteoporosis

G Gargano, G Asparago, F Spiezia, F Oliva… - British Medical …, 2023 - academic.oup.com
Background Osteoporosis results in reduced bone mass and consequent bone fragility.
Small interfering RNAs (siRNAs) can be used for therapeutic purposes, as molecular targets …

[HTML][HTML] Proximal femoral fractures in the elderly: a few things to know, and some to forget

N Maffulli, R Aicale - Medicina, 2022 - mdpi.com
Hip fractures are a leading cause of hospitalisation in elderly patients, representing an
increasing socioeconomic problem arising from demographic changes, considering the …

[HTML][HTML] Expert consensus on the bone repair strategy for osteoporotic fractures in China

H Zhang, Y Hu, X Chen, S Wang, L Cao… - Frontiers in …, 2022 - frontiersin.org
Osteoporotic fractures, also known as fragility fractures, are prevalent in the elderly and
bring tremendous social burdens. Poor bone quality, weak repair capacity, instability, and …

[HTML][HTML] Predictors of osteoporotic fracture in postmenopausal women: a meta-analysis

G Long, C Liu, T Liang, Z Zhang, Z Qin… - Journal of Orthopaedic …, 2023 - Springer
Osteoporosis affects more than 200 million women worldwide, with postmenopausal women
being particularly susceptible to this condition and its severe sequelae disproportionately …

[HTML][HTML] Bioinformatics and machine learning were used to validate glutamine metabolism-related genes and immunotherapy in osteoporosis patients

L Wang, C Deng, Z Wu, K Zhu, Z Yang - Journal of Orthopaedic Surgery …, 2023 - Springer
Background Osteoporosis (OP), often referred to as the “silent disease of the twenty-first
century,” poses a significant public health concern due to its severity, chronic nature, and …

[HTML][HTML] Comparison between calcaneus quantitative ultrasound and the gold standard DXA in the ability to detect osteoporosis in chronic obstructive pulmonary …

W Chanprasertpinyo, C Punsawad… - Journal of Orthopaedic …, 2023 - Springer
Background Osteoporosis is a prevalent comorbidity in patients with COPD that is usually
underrecognized and hence, undertreated. Compared to the gold standard dual-energy X …

Pharmacological agents for bone fracture healing: talking points from recent clinical trials

F Migliorini, F Cocconi, G Vecchio… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Pharmacological strategies might influence bone healing in terms of time to
union or quality of mature bone. This expert opinion discussed the current level I evidence …

[HTML][HTML] MRI-based vertebral bone quality score for the assessment of osteoporosis in patients undergoing surgery for lumbar degenerative diseases

Z Chen, F Lei, F Ye, H Yuan, S Li, D Feng - Journal of Orthopaedic Surgery …, 2023 - Springer
Purpose To explore the value of vertebral bone quality (VBQ) scores in diagnosing
osteoporosis in patients with lumbar degeneration. Methods A retrospective analysis was …

[HTML][HTML] Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology

F Zhu, W Li, L Wang, B Dai, Z Liu, H Wu… - Journal of Orthopaedic …, 2023 - Springer
Abstract Background Liuwei Dihuang Pill (LP) was verified to alleviate postmenopausal
osteoporosis (PMOP) development. Nevertheless, the major constituent of LP and the …

[HTML][HTML] Secoisolariciresinol diglucoside regulates estrogen receptor expression to ameliorate OVX-induced osteoporosis

G Chen, Y Chen, J Hong, J Gao, Z Xu - Journal of Orthopaedic Surgery …, 2023 - Springer
Objective Secoisolariciresinol diglucoside (SDG) is a phytoestrogen that has been reported
to improve postmenopausal osteoporosis (PMOP) caused by estrogen deficiency. In our …