Simple Summary The survival rate for pediatric cancers has improved significantly over the
last decades. Conventional chemotherapies play a vital role in pediatric cancer treatment …

The therapy design of childhood acute lymphoblastic leukemia (ALL) has evolved over the
past 60 years. The St. Jude Children's Research Hospital has developed 17 treatment …

Cancer is a worldwide public health priority with a high socioeconomic burden.
Unfortunately, cancer treatments often lead to side effects and impairments, greatly feared …

Increased glycolytic metabolism plays an important role in B-cell precursor Acute
Lymphoblastic Leukemia (BCP-ALL). We previously showed that IGFBP7 exerts mitogenic …

The benefit associated with the incorporation of vincristine-corticosteroid pulses in
maintenance therapy for pediatric acute lymphoblastic leukemia (ALL) is unclear …

Acute lymphoblastic leukemia (ALL) is the most common cancer in children worldwide.
Although ALL patients' overall survival rates in wealthy countries currently surpass 80%, 15 …

The advances in pediatric acute lymphoblastic leukemia (ALL) care have substantially
increased survival, and the late effects of treatment are a growing concern. Obesity …

Acute lymphoblastic leukemia (ALL) and its treatment continue to pose substantial risks. To
understand ALL more deeply, the metabolome in fasting plasma of 27 ALL patients before …

Simple Summary B-cell acute lymphoblastic leukemia (B-ALL) is the most common form of
cancer in children. Current treatments deliver a high survival rate, but often cause harmful …

Surgery, chemotherapy and radiation have been the mainstay of pediatric brain tumor
treatment over the past decades. Recently, new treatment modalities have emerged for the …