[HTML][HTML] Role of oxidative stress and inflammation-related signaling pathways in doxorubicin-induced cardiomyopathy

S Shi, Y Chen, Z Luo, G Nie, Y Dai - Cell Communication and Signaling, 2023 - Springer
Doxorubicin (DOX) is a powerful and commonly used chemotherapeutic drug, used alone or
in combination in a variety of cancers, while it has been found to cause serious cardiac side …

[HTML][HTML] Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment

S Whelan, B Lucey, K Finn - Microorganisms, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections, especially
among women and older adults, leading to a significant global healthcare cost burden …

[HTML][HTML] HIV–host cell interactions

SK Masenga, BC Mweene, E Luwaya, L Muchaili… - Cells, 2023 - mdpi.com
The development of antiretroviral drugs (ARVs) was a great milestone in the management of
HIV infection. ARVs suppress viral activity in the host cell, thus minimizing injury to the cells …

Osteoimmunology in periodontitis and orthodontic tooth movement

B Alghamdi, HH Jeon, J Ni, D Qiu, A Liu… - Current osteoporosis …, 2023 - Springer
Abstract Purpose of Review To review the role of the immune cells and their interaction with
cells found in gingiva, periodontal ligament, and bone that leads to net bone loss in …

Inflammasomes in neurological disorders—mechanisms and therapeutic potential

KA Ravichandran, MT Heneka - Nature Reviews Neurology, 2024 - nature.com
Inflammasomes are molecular scaffolds that are activated by damage-associated and
pathogen-associated molecular patterns and form a key element of innate immune …

[HTML][HTML] Molecular mechanisms for the vicious cycle between insulin resistance and the inflammatory response in obesity

D Szukiewicz - International Journal of Molecular Sciences, 2023 - mdpi.com
The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

[HTML][HTML] Protein-based adjuvants for vaccines as immunomodulators of the innate and adaptive immune response: Current knowledge, challenges, and future …

DA Díaz-Dinamarca, ML Salazar, BN Castillo… - Pharmaceutics, 2022 - mdpi.com
New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic
than classical vaccines formulated with live-attenuated or inactivated pathogens. This …

[HTML][HTML] Interaction between microbiota and immunity and its implication in colorectal cancer

C Xing, Y Du, T Duan, K Nim, J Chu, HY Wang… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world.
Besides genetic causes, colonic inflammation is one of the major risk factors for CRC …

Revolutionizing medicine with toll-like receptors: A path to strengthening cellular immunity

JA Malik, G Kaur, JN Agrewala - International Journal of Biological …, 2023 - Elsevier
Toll-like receptors play a vital role in cell-mediated immunity, which is crucial for the immune
system's defense against pathogens and maintenance of homeostasis. The interaction …

[HTML][HTML] Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models

KM Ibrahim, SF Darwish, EM Mantawy… - Molecular and Cellular …, 2023 - Springer
Cyclophosphamide has drastically enhanced the expectancy and quality of life of cancer
patients. However, it is accompanied by diverse neurological complications which are …