Heterogeneity in pulmonary microvascular blood flow (perfusion) provides an early indicator
of lung disease or disease susceptibility. However, most computational models of the …

Background The effect of body position on the generation of abnormal respiratory sounds
(eg, snoring and stridor) is well recognized. Postural effects on normal lung sounds have …

Prone positioning is frequently used for non-intubated hypoxemic patients with COVID-19,
although conclusive evidence is still lacking. The aim of the present study was to investigate …

Purpose To present a method for simultaneous acquisition of alveolar oxygen tension
(PAO2), specific ventilation (SV), and apparent diffusion coefficient (ADC) of hyperpolarized …

Background Lower fractional inspired oxygen tension (Fio2) during general anesthesia can
reduce lung atelectasis. The objectives are to evaluate the effect of two Fio2 (0.4 and 1) …

Despite a huge range in lung size between species, there is little measured difference in the
ability of the lung to provide a well-matched air flow (ventilation) to blood flow (perfusion) at …

Gravity and matched airway/vascular tree geometries are both hypothesized to be key
contributors to ventilation-perfusion (V̇/Q̇) matching in the lung, but their relative …

Respiratory disease is a significant problem worldwide, and it is a problem with increasing
prevalence. Pathology in the upper airways and lung is very difficult to diagnose and treat …

Background Without aggressive treatment, pulmonary arterial hypertension (PAH) has a 5-
year mortality of approximately 40%. A patient's response to vasodilators at diagnosis …

We have developed a novel functional proton magnetic resonance imaging (MRI) technique
to measure regional ventilation-perfusion (V̇A/Q̇) ratio in the lung. We conducted a …