Cardiovascular disease and COPD: dangerous liaisons?

KF Rabe, JR Hurst, S Suissa - European Respiratory Review, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently occur together and their coexistence is associated with worse outcomes than …

Diagnosis and outpatient management of chronic obstructive pulmonary disease: a review

CM Riley, FC Sciurba - Jama, 2019 - jamanetwork.com
Importance There are 30 million adults (12%) in the United States who have chronic
obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease accounts for …

Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised …

A Papi, J Vestbo, L Fabbri, M Corradi, H Prunier… - The Lancet, 2018 - thelancet.com
Background Evidence is scarce on the relative risk-benefit of inhaled triple therapy,
consisting of inhaled corticosteroid, long-acting muscarinic antagonist, and long-acting β 2 …

Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - ASPET
Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

Diagnostic and therapeutic gaps in patients with heart failure and chronic obstructive pulmonary disease

M Canepa, FME Franssen, H Olschewski, M Lainscak… - JACC: Heart Failure, 2019 - jacc.org
Heart failure (HF) and chronic obstructive pulmonary disease (COPD) coincide in a
significant number of patients. Recent population-based registries suggest that spirometry is …

Clinical approach to the therapy of asthma-COPD overlap

DJ Maselli, M Hardin, SA Christenson, NA Hanania… - Chest, 2019 - Elsevier
Over the last few years, there has been a renewed interest in patients with characteristics of
both asthma and COPD. Although the precise definition of asthma-COPD overlap (ACO) is …

Screening for chronic obstructive pulmonary disease: updated evidence report and systematic review for the US Preventive Services Task Force

EM Webber, JS Lin, RG Thomas - Jama, 2022 - jamanetwork.com
Importance Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality in the US. Objective To conduct a targeted systematic review to update the …

Pharmacological mechanisms leading to synergy in fixed-dose dual bronchodilator therapy

L Calzetta, MG Matera, M Cazzola - Current Opinion in Pharmacology, 2018 - Elsevier
Highlights•Dual bronchodilator therapy has clinical benefits in COPD.•Combining a LABA
with a LAMA synergistically relaxes medium and small airways.•In some approved …

Multimorbidity clusters in patients with chronic obstructive airway diseases in the EpiChron Cohort

J Carmona-Pírez, B Poblador-Plou, I Ioakeim-Skoufa… - Scientific Reports, 2021 - nature.com
Chronic obstructive airway diseases such as chronic obstructive pulmonary disease
(COPD), asthma, rhinitis, and obstructive sleep apnea (OSA) are amongst the most common …

Increased risk of major adverse cardiac events following the onset of acute exacerbations of COPD

M Reilev, A Pottegård, J Lykkegaard… - …, 2019 - Wiley Online Library
Background and objective Acute exacerbations in chronic obstructive pulmonary disease
(COPD) may trigger major adverse cardiac events (MACE). We aimed to determine whether …