[HTML][HTML] Cardiovascular safety of revefenacin, a once-daily, lung-selective, long-acting muscarinic antagonist for nebulized therapy of chronic obstructive pulmonary …

JF Donohue, G Feldman, S Sethi, CN Barnes… - Pulmonary …, 2019 - Elsevier
The cardiovascular safety of revefenacin, an anticholinergic indicated for the maintenance
treatment of patients with chronic obstructive lung disease (COPD), was evaluated in phase …

Tiotropium bromide, a long acting muscarinic receptor antagonist triggers intracellular calcium signalling in the heart

S Cassambai, CJ Mee, D Renshaw… - Toxicology and Applied …, 2019 - Elsevier
Background and purpose Tiotropium bromide (TB) is a long acting muscarinic receptor
antagonist used to manage chronic obstructive pulmonary disease (COPD). Recent meta …

Multidisciplinary management of patients with chronic obstructive pulmonary disease and cardiovascular disease

J de Miguel-Díez, JN Villota, SS Pérez… - Archivos de …, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently coexist, increasing the prevalence of both entities and impacting on symptoms …

Chronic obstructive pulmonary disease research by using big data

CK Rhee - The Clinical Respiratory Journal, 2021 - Wiley Online Library
As the information technology develops, large amount of data has been stored. The
digitalisation of the health‐care system enables researchers to use big data easily. Big data …

Risks of maternal cardiopulmonary events associated with ritodrine for tocolysis: A national database linkage study in 1 831 564 pregnant women

CW Lin, KA Chan, YY Chen, WI Huang… - … of Gynecology & …, 2024 - Wiley Online Library
Objective Real‐world data on cardiopulmonary events among pregnant women receiving β‐
agonist therapy are scarce. In the present study, we aimed to examine the absolute and …

Resveratrol prevents skeletal muscle atrophy and senescence via regulation of histone deacetylase 2 in cigarette smoke-induced mice with emphysema

C Li, ZH Deng, GX Zheng, T Xie, XY Wei… - Journal of …, 2022 - Taylor & Francis
Objective The aim of this study was to investigate the effects of resveratrol (RSV) on cigarette
smoke (CS)-induced skeletal muscle atrophy and senescence in mice with emphysema and …

[HTML][HTML] Development of Risk Prediction Model for Muscular Calf Vein Thrombosis with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

X Hu, X Li, H Xu, W Zheng, J Wang… - … Journal of General …, 2022 - ncbi.nlm.nih.gov
Purpose This study aims to establish a risk prediction model for muscular calf vein
thrombosis (MCVT) in patients with acute exacerbation of chronic obstructive pulmonary …

Is the use of two versus one long-acting bronchodilator by patients with COPD associated with a higher risk of acute coronary syndrome in real-world clinical practice?

L Parkin, S Williams, D Barson… - BMJ Open …, 2021 - bmjopenrespres.bmj.com
Background Cardiovascular comorbidity is common among patients with chronic obstructive
pulmonary disease (COPD) and there is concern that long-acting bronchodilators (long …

Current evidence for COPD management with dual long-acting muscarinic antagonist/long-acting β2-agonist bronchodilators

NS Skolnik, TS Nguyen, A Shrestha, R Ray… - Postgraduate …, 2020 - Taylor & Francis
Long-acting inhaled bronchodilator medications are recommended as initial maintenance
therapy for many patients with COPD. These medications include long-acting muscarinic …

Use of prescription medications with cardiovascular adverse effects among older adults in the United States

K Ozenberger, GC Alexander, JI Shin… - … and Drug Safety, 2022 - Wiley Online Library
Background Many commonly used prescription medications have cardiovascular adverse
effects, yet the cumulative risk of cardiovascular events associated with the concurrent use of …