[HTML][HTML] Normalization of the tumor microenvironment by harnessing vascular and immune modulation to achieve enhanced cancer therapy
Y Choi, K Jung - Experimental & Molecular Medicine, 2023 - nature.com
Solid tumors are complex entities that actively shape their microenvironment to create a
supportive environment for their own growth. Angiogenesis and immune suppression are …
supportive environment for their own growth. Angiogenesis and immune suppression are …
[HTML][HTML] Engineering materials for pyroptosis induction in cancer treatment
J Liu, T Chen, XL Liu, ZH Li, Y Zhang - Bioactive Materials, 2024 - Elsevier
Cancer remains a significant global health concern, necessitating the development of
innovative therapeutic strategies. This research paper aims to investigate the role of …
innovative therapeutic strategies. This research paper aims to investigate the role of …
[HTML][HTML] Radiotherapy-activated NBTXR3 nanoparticles promote ferroptosis through induction of lysosomal membrane permeabilization
J Da Silva, C Bienassis, P Schmitt, C Berjaud… - Journal of Experimental …, 2024 - Springer
Abstract Purpose Radiotherapy-activated NBTXR3 (NBTXR3+ RT) has demonstrated
superior efficacy in cancer cell destruction and tumor growth control, compared to …
superior efficacy in cancer cell destruction and tumor growth control, compared to …
[HTML][HTML] Opaganib (ABC294640) Induces Immunogenic Tumor Cell Death and Enhances Checkpoint Antibody Therapy
LW Maines, SN Keller, CD Smith - International Journal of Molecular …, 2023 - mdpi.com
Antibody-based cancer drugs that target the checkpoint proteins CTLA-4, PD-1 and PD-L1
provide marked improvement in some patients with deadly diseases such as lung cancer …
provide marked improvement in some patients with deadly diseases such as lung cancer …
Emerging role of immunogenic cell death in cancer immunotherapy
Cancer immunotherapy, such as immune checkpoint blockade (ICB), has emerged as a
groundbreaking approach for effective cancer treatment. Despite its considerable potential …
groundbreaking approach for effective cancer treatment. Despite its considerable potential …
Apoptosis‐Sensitizing Tumor Nanomedicine by Regulating Pyroptosis‐Associated Inflammatory Cell Death
F Du, H Zhao, Y Song, Z Feng, K Liu… - Advanced Functional …, 2024 - Wiley Online Library
The vigorous development of cancer nanomedicine has revolutionized traditional oncology
medicine, but it is also limited by the continuous mutation of cunning cancer cells, leading to …
medicine, but it is also limited by the continuous mutation of cunning cancer cells, leading to …
Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment
Q Yin, SY Song, Y Bian, Y Wang, A Deng, J Lv… - Frontiers in …, 2024 - frontiersin.org
Background The interaction between pyroptosis—a form of programmed cell death—and
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …
[HTML][HTML] Nano-Delivery of Immunogenic Cell Death Inducers and Immune Checkpoint Blockade Agents: Single-Nanostructure Strategies for Enhancing …
Cancer immunotherapy has revolutionized oncology by harnessing the patient's immune
system to target and eliminate cancer cells. However, immune checkpoint blockades (ICBs) …
system to target and eliminate cancer cells. However, immune checkpoint blockades (ICBs) …
[HTML][HTML] Uncovering the colorectal cancer immunotherapeutic potential: Evening primrose (Oenothera biennis) root extract and its active compound oenothein B …
EJ Lee, YS Kim, JH Kim, KW Woo, YH Park, JH Ha… - Phytomedicine, 2024 - Elsevier
Background The emergence of immune checkpoint inhibitors, a novel class of
immunotherapy drugs, represents a major breakthrough in cancer immunotherapy …
immunotherapy drugs, represents a major breakthrough in cancer immunotherapy …
[HTML][HTML] Nanotechnology-Assisted Immunogenic Cell Death for Effective Cancer Immunotherapy
Y Guo, R Ma, M Zhang, Y Cao, Z Zhang, W Yang - Vaccines, 2023 - mdpi.com
Tumor vaccines have been used to treat cancer. How to efficiently induce tumor-associated
antigens (TAAs) secretion with host immune system activation is a key issue in achieving …
antigens (TAAs) secretion with host immune system activation is a key issue in achieving …