[HTML][HTML] Molecular machinery and interplay of apoptosis and autophagy in coronary heart disease

Y Dong, H Chen, J Gao, Y Liu, J Li, J Wang - Journal of molecular and …, 2019 - Elsevier
Coronary heart disease (CHD) is a common heart disease and the leading cause of
cardiovascular death. Apoptosis and autophagy are two forms of programmed cell deaths …

A meta-analysis of microRNA expression profiling studies in heart failure

A Gholaminejad, N Zare, N Dana, D Shafie, A Mani… - Heart Failure …, 2021 - Springer
Heart failure (HF) is a major consequence of many cardiovascular diseases with high rate of
morbidity and mortality. Early diagnosis and prevention are hampered by the lack of …

[HTML][HTML] COVID-19 virulence in aged patients might be impacted by the host cellular microRNAs abundance/profile

S Fulzele, B Sahay, I Yusufu, TJ Lee, A Sharma… - Aging and …, 2020 - ncbi.nlm.nih.gov
The World health organization (WHO) declared Coronavirus disease 2019 (COVID-19) a
global pandemic and a severe public health crisis. Drastic measures to combat COVID-19 …

Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing …

M Liu, M Su, D Tang, L Hao, XH Xun… - BMC Pulmonary Medicine, 2019 - Springer
Background Reactive oxygen species (ROS) levels largely determine pulmonary fibrosis.
Antioxidants have been found to ameliorate lung fibrosis after long-term paraquat (PQ) …

Emerging role of mTOR signaling‐related miRNAs in cardiovascular diseases

A Samidurai, RC Kukreja, A Das - Oxidative medicine and …, 2018 - Wiley Online Library
Mechanistic/mammalian target of rapamycin (mTOR), an atypical serine/threonine kinase of
the phosphoinositide 3‐kinase‐(PI3K‐) related kinase family, elicits a vital role in diverse …

Integrated Analysis of lncRNA–miRNA–mRNA Regulatory Network in Rapamycin-Induced Cardioprotection against Ischemia/Reperfusion Injury in Diabetic Rabbits

A Samidurai, AL Olex, R Ockaili, D Kraskauskas… - Cells, 2023 - mdpi.com
The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides
protection against myocardial ischemia/reperfusion (I/R) injury in diabetes. Since …

miR‐30e‐3p Promotes Cardiomyocyte Autophagy and Inhibits Apoptosis via Regulating Egr‐1 during Ischemia/Hypoxia

B Su, X Wang, Y Sun, M Long, J Zheng… - BioMed Research …, 2020 - Wiley Online Library
Background. Microvascular obstruction (MVO) can result in coronary microcirculation
embolism and myocardial microinfarction. Myocardial injury induced by MVO is …

Inhibition of long non-coding RNA KCNQ1OT1 attenuates neuroinflammation and neuronal apoptosis through regulating NLRP3 expression via sponging miR-30e-3p

A Song, Y Yang, H He, J Sun, Q Chang… - Journal of Inflammation …, 2021 - Taylor & Francis
Background Neuroinflammation and neuronal apoptosis are considered as the critical
factors in the pathogenesis of multiple neurological diseases. Recent studies have shown …

Diabetes and COVID-19 risk: an miRNA perspective

PK Mishra, R Tandon… - American Journal of …, 2020 - journals.physiology.org
Coronavirus disease 2019 (COVID-19) and diabetes outcomes (CORONADO) trial revealed
that 10.6% of patients with diabetes mellitus hospitalized for COVID-19 (COVID-19) die …

[HTML][HTML] Pim1 overexpression prevents apoptosis in cardiomyocytes after exposure to hypoxia and oxidative stress via upregulating cell autophagy

H Zhu, X Wang, Y Sun, W He, J Liang, B Mo… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Microvascular obstruction (MVO), an undesirable complication of
percutaneous coronary intervention, is independently associated with adverse left ventricle …