Peripheral mediators can contribute to the development and maintenance of inflammatory
and neuropathic pain and its concomitants (hyperalgesia and allodynia) via two …

Inflammation, and the pain that accompanies it, is a natural response of the body. The
licorice plant (Glycyrrhiza glabra) have demonstrated anti-inflammatory, anti-edematous …

The antinociceptive effects of the endocannabinoids (ECs) are enhanced by inhibiting
catabolic enzymes such as fatty acid amide hydrolase (FAAH). The physiological relevance …

The present study was designed to evaluate the antinociceptive profile of caffeic acid in mice
and rats. Caffeic acid (5–100 mg/kg, po), in a dose dependent manner inhibited acetic acid …

Muntingia calabura L.(family Elaeocarpaceae) has been traditionally used to relieve various
pain‐related ailments. The present study aimed to determine the antinociceptive activity of …

Abstract Objectives Carvacrol (5-isopropyl-2-methylphenol) is a monoterpenic phenol which
is present in the essential oil of oregano and thyme. We have investigated the behavioural …

Aim of the study Antinociceptive activity of Rhoifoline A (RA), a benzophenanthridine
alkaloid obtained from the ethanol extract of Zanthoxylum nitidum, was evaluated in mice …

Formalin (0.25, 0.5, 3, and 5%) injected into the knee joint of rats induced a dose-dependent
nociception that was featured by 2 phases of intense guarding behavior of the affected limb …

Antinociceptive activity of Paederosidic Acid Methyl Ester (PAME), a chemical compound
isolated from the n-butanol fraction of Paederia scandens, was evaluated in mice using …

Objective Previous studies have found that sildenafil produces antinociception in
experimental models. This work was undertaken to determine the participation of the …