Penicillin allergy

M Castells, DA Khan, EJ Phillips - New England Journal of …, 2019 - Mass Medical Soc
Penicillin Allergy Many more patients are labeled as penicillin-allergic than actually are
allergic. The label should be analyzed with skin testing and test exposure. Patients with true …

The challenge of de‐labeling penicillin allergy

CA Stone Jr, J Trubiano, DT Coleman, CRF Rukasin… - Allergy, 2020 - Wiley Online Library
Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

[HTML][HTML] 2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines

FER Simons, M Ebisawa, M Sanchez-Borges… - World Allergy …, 2015 - Elsevier
Abstract The World Allergy Organization (WAO) Guidelines for the assessment and
management of anaphylaxis provide a unique global perspective on this increasingly …

Consequences of avoiding β-lactams in patients with β-lactam allergies

MN Jeffres, PP Narayanan, JE Shuster… - Journal of Allergy and …, 2016 - Elsevier
Background The choice of empiric antibiotics for the treatment of gram-negative bacilli
(GNB) bloodstream infections (BSIs) in patients presenting with a β-lactam (BL) allergy is …

[HTML][HTML] The cost of self-reported penicillin allergy: a systematic review

TJ Mattingly II, A Fulton, RA Lumish… - The Journal of Allergy …, 2018 - Elsevier
Background Patients who report a penicillin (PCN) allergy receive suboptimal antibiotic
therapy compared with patients not reporting an allergy. However, a majority of patients who …

[HTML][HTML] Guideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics: guideline of the German Society for Allergology and Clinical …

G Wurpts, W Aberer, H Dickel, R Brehler… - Allergo Journal …, 2019 - Springer
This guideline on diagnostic procedures for suspected beta-lactam antibiotic (BLA)
hypersensitivity was written by the German and Austrian professional associations for …

Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge: a systematic review

L Cooper, J Harbour, J Sneddon… - JAC-Antimicrobial …, 2021 - academic.oup.com
Background Approximately 10% of people have an unverified penicillin allergy, with multiple
personal and public health consequences. Objectives To assess the efficacy and safety of …

The cost of penicillin allergy evaluation

KG Blumenthal, Y Li, A Banerji, BJ Yun, AA Long… - The Journal of Allergy …, 2018 - Elsevier
Background Unverified penicillin allergy leads to adverse downstream clinical and
economic sequelae. Penicillin allergy evaluation can be used to identify true, IgE-mediated …

Penicillin allergy testing is cost-saving: an economic evaluation study

B Sousa-Pinto, KG Blumenthal, E Macy… - Clinical Infectious …, 2021 - academic.oup.com
Background Having a penicillin allergy label is associated with the use of less appropriate
and more expensive antibiotics and increased healthcare utilization. Penicillin allergy …

[HTML][HTML] The high impact of penicillin allergy registration in hospitalized patients

SM van Dijk, H Gardarsdottir, MWM Wassenberg… - The Journal of Allergy …, 2016 - Elsevier
Background Suspected penicillin allergy (Pen-A) is often not verified or excluded by
diagnostic testing. Objective To assess the prevalence and impact of Pen-A registration in a …