Antioxidant and anti-inflammatory properties of resveratrol in diabetic nephropathy: a systematic review and meta-analysis of animal studies

HC Hu, YH Lei, WH Zhang, XQ Luo - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Accumulated experimental evidence suggests that resveratrol may have an
effect on diabetic nephropathy by inhibiting inflammation and decreasing oxidative stress …

An updated pharmacological insight of resveratrol in the treatment of diabetic nephropathy

KX Li, MJ Ji, HJ Sun - Gene, 2021 - Elsevier
As one of the most common complications of diabetes, nephropathy develops in
approximately 40% of diabetic individuals. Although end stage kidney disease is known as …

Autophagy and its therapeutic potential in diabetic nephropathy

YP Han, LJ Liu, JL Yan, MY Chen, XF Meng… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is the most
significant microvascular complication of diabetes and poses a severe public health concern …

Chinese herbal medicine and its active compounds in attenuating renal injury via regulating autophagy in diabetic kidney disease

P Liu, W Zhu, Y Wang, G Ma, H Zhao… - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is the main cause of end-stage renal disease worldwide, and
there is a lack of effective treatment strategies. Autophagy is a highly conserved lysosomal …

[HTML][HTML] Traditional Chinese medicine compounds ameliorating glomerular diseases via autophagy: a mechanism review

X Shi, M Chang, M Zhao, Y Shi, Y Zhang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Glomerular diseases are major components of kidney disease, mainly manifested as
podocyte disease, immune complex-associated glomerulonephritis, and renal autoimmune …

Identification and validation of immune-related biomarkers and potential regulators and therapeutic targets for diabetic kidney disease

S Chen, B Li, L Chen, H Jiang - BMC Medical Genomics, 2023 - Springer
Background Diabetic kidney disease (DKD) is a major complication of diabetes and the
leading cause of end-stage renal disease worldwide. Renal inflammation and infiltration of …

Molecular mechanistic pathways targeted by natural compounds in the prevention and treatment of diabetic kidney disease

K Zhou, X Zi, J Song, Q Zhao, J Liu, H Bao, L Li - Molecules, 2022 - mdpi.com
Diabetic kidney disease (DKD) is one of the most common complications of diabetes, and its
prevalence is still growing rapidly. However, the efficient therapies for this kidney disease …

Histological and biochemical investigation of the renoprotective effects of metformin in diabetic and prostate cancer model

P Koroglu-Aydın, BB Bayrak, I Bugan… - Toxicology …, 2021 - Taylor & Francis
Background Diabetes and cancer have common physiological and biochemical
mechanisms. Metformin is the preferred drug of choice for the treatment of diabetes. Prostate …

[HTML][HTML] The combinational effect of inulin and resveratrol on the oxidative stress and inflammation level in a rat model of diabetic nephropathy

F Ghavidel, H Amiri, MH Tabrizi, S Alidadi… - Current Developments …, 2024 - Elsevier
Background Using inulin can enhance resveratrol's effects by improving the intestinal
microbiome and the stability of resveratrol. Objectives We aimed to investigate the effect of …

[HTML][HTML] Silencing of METTL3 prevents the proliferation, migration, epithelial-mesenchymal transition, and renal fibrosis of high glucose-induced HK2 cells by …

Y Chen, P Li, M Lin, Y Jiang, G Tan, L Huang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is one of the most serious complications in diabetic patients. And
m6A modifications mediated by METTL3 are involved multiple biological processes …