OTU domain-containing ubiquitin aldehyde-binding proteins 1 (OTUB1) is the most
important element of the deubiquitinase OTU superfamily, which has been identified as an …

Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by
recurrent vascular thrombosis and miscarriages in the absence of known causes. Antibodies …

Vein thrombosis is one of the most serious types of cardiovascular disease. During the
traditional treatment, due to the excessive blood flow rate, the drug utilization rate at the …

Highlights•17 batches of commercial leeches were identified using DNA barcoding based
on COI gene.•A total of 1035 proteins were identified from 3 species leeches.•90 co-existed …

The complement system is part of the innate immune system. The crucial step in activating
the complement system is the generation and regulation of C3 convertase complexes, which …

Coagulation factor XI (FXI) has increasingly been shown to play an integral role in several
physiologic and pathological processes. FXI is among several zymogens within the blood …

Platelets are important cellular targets in cardiovascular disease. Based on insights from
basic science, translational approaches and clinical studies, a distinguished anti-platelet …

P2X receptors belong to a family of cation channel proteins, which respond to extracellular
adenosine 5′-triphosphate (ATP). These receptors have gained increasing attention in …

Intramuscular fat (IMF) content is a key determinant of pork quality. Controlling the genetic
and physiological factors of IMF and the expression patterns of various genes is important …

The Coronavirus Disease 2019 (COVID-19) showed worse prognosis and higher mortality in
individuals with obesity. Dyslipidemia is a major link between obesity and COVID-19 …