Tumour-associated macrophages: versatile players in the tumour microenvironment
ZZ Ji, MKK Chan, ASW Chan, KT Leung… - Frontiers in Cell and …, 2023 - frontiersin.org
Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …
Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging …
Lung cancer remains the leading cause of cancer-related deaths globally, and the survival
rate remains low despite advances in diagnosis and treatment. The progression of lung …
rate remains low despite advances in diagnosis and treatment. The progression of lung …
Synergistic efficacy of simultaneous anti-TGF-β/VEGF bispecific antibody and PD-1 blockade in cancer therapy
M Niu, M Yi, Y Wu, L Lyu, Q He, R Yang, L Zeng… - Journal of Hematology & …, 2023 - Springer
Background Recently, therapeutic antibodies against programmed cell death 1 (PD-1) and
its ligand (PD-L1) have exerted potent anticancer effect in a variety of tumors. However …
its ligand (PD-L1) have exerted potent anticancer effect in a variety of tumors. However …
VEGF signaling: Role in angiogenesis and beyond
P Shaw, SKD Dwivedi, R Bhattacharya… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Angiogenesis is a crucial process for tissue development, repair, and tumor survival.
Vascular endothelial growth factor (VEGF) is a key driver secreted by cancer cells …
Vascular endothelial growth factor (VEGF) is a key driver secreted by cancer cells …
Changing landscape of anti-angiogenic therapy: Novel approaches and clinical perspectives
RN Gacche - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Targeting angiogenesis has remained one of the important aspects in disease biology in
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …
Anticancer activity and other biomedical properties of β‐sitosterol: Bridging phytochemistry and current pharmacological evidence for future translational approaches
Sterols, including β‐sitosterol, are essential components of cellular membranes in both plant
and animal cells. Despite being a major phytosterol in various plant materials …
and animal cells. Despite being a major phytosterol in various plant materials …
The post-chemotherapy changes of tumor physical microenvironment: targeting extracellular matrix to address chemoresistance
The tumor physical microenvironment (TPME) contributes to cancer chemoresistance in both
mechanical and mechanobiological approaches. Along with chemotherapy, the tumor …
mechanical and mechanobiological approaches. Along with chemotherapy, the tumor …
Cancer stem cells: advances in knowledge and implications for cancer therapy
X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs
S Shao, H Miao, W Ma - Frontiers in Immunology, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) are integral to the tumor microenvironment (TME),
influencing cancer progression significantly. Attracted by cancer cell signals, TAMs exhibit …
influencing cancer progression significantly. Attracted by cancer cell signals, TAMs exhibit …
Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy
Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …