Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system (CNS) manifested with varying clinical course, pathology, and inflammatory patterns …

Multiple sclerosis (MS) is the principal cause of autoimmune neuroinflammation in humans,
and its animal model, experimental autoimmune encephalomyelitis (EAE), is widely used to …

This protocol details a method to actively induce experimental allergic encephalomyelitis
(EAE), a widely used animal model for studies of multiple sclerosis. EAE is induced by …

Multiple sclerosis is an inflammatory, demyelinating disease of the central nervous system
(CNS) characterized by a wide range of clinical signs. The location of lesions in the CNS is …

The interleukin (IL)-12p40 family of cytokines plays a critical role in the development of
experimental autoimmune encephalomyelitis (EAE). However, the relative contributions of IL …

Traumatic brain injury (TBI) leaves many survivors with long-term disabilities. A prolonged
immune response in the brain may cause neurodegeneration, resulting in chronic …

We describe new T cell receptor (TCR) transgenic mice (relapsing-remitting [RR] mice)
carrying a TCR specific for myelin oligodendrocyte glycoprotein (MOG) peptide 92–106 in …

Experimental allergic encephalomyelitis (EAE) is a widely used animal model of the human
demyelinating disease multiple sclerosis. EAE is initiated by immunization with myelin …

The ELR+ CXC chemokines CXCL1 and CXCL2 are up-regulated in the central nervous
system (CNS) during multiple sclerosis (MS) and its animal model, experimental …

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system that is believed to have an autoimmune etiology. As MS is the most common …