Natural products against renin-angiotensin system for antifibrosis therapy
T Yang, YY Chen, JR Liu, H Zhao, ND Vaziri… - European journal of …, 2019 - Elsevier
Fibrosis is a final pathological feature of many chronic diseases, but few interventions are
available that specifically target the pathogenesis of fibrosis. The highlights of common …
available that specifically target the pathogenesis of fibrosis. The highlights of common …
[HTML][HTML] Pathophysiological role of osteopontin and angiotensin II in atherosclerosis
Y Ding, J Chen, G Cui, Y Wei, C Lu, L Wang… - … and biophysical research …, 2016 - Elsevier
Highlights•This review includes some new mechanisms of Atherosclerosis.•In the context of
atherosclerosis, OPN and Ang II is generally regarded as a proinflammatory and …
atherosclerosis, OPN and Ang II is generally regarded as a proinflammatory and …
[HTML][HTML] Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction
A Han, Y Lu, Q Zheng, J Zhang, YZ Zhao… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has been
demonstrated to be effective and safe for the treatment of chronic heart failure. Left …
demonstrated to be effective and safe for the treatment of chronic heart failure. Left …
Acute hyperthermia inhibits TGF-β1-induced cardiac fibroblast activation via suppression of Akt signaling
M Narikawa, M Umemura, R Tanaka, T Fujita… - Scientific reports, 2018 - nature.com
Transforming growth factor-β1 (TGF-β1) induces phenotypic changes in fibroblasts to
become myofibroblasts with increased production of extracellular matrix (ECM) components …
become myofibroblasts with increased production of extracellular matrix (ECM) components …
Systematic screening and characterization of Qi-Li-Qiang-Xin capsule-related xenobiotics in rats by ultra-performance liquid chromatography coupled with quadrupole …
W Yun, Z Yao, C Fan, Z Qin, X Tang, M Gao… - … of Chromatography B, 2018 - Elsevier
Abstract Qi-Li-Qiang-Xin capsule (QLQX), a well-known traditional Chinese medicine
prescription (TCMP), is consisted of eleven commonly used herbal medicines, has been …
prescription (TCMP), is consisted of eleven commonly used herbal medicines, has been …
Qiliqiangxin: A multifaceted holistic treatment for heart failure or a pharmacological probe for the identification of cardioprotective mechanisms?
M Packer - European Journal of Heart Failure, 2023 - Wiley Online Library
The active ingredients in many traditional Chinese medicines are isoprene oligomers with a
diterpenoid or triterpenoid structure, which exert cardiovascular effects by signalling through …
diterpenoid or triterpenoid structure, which exert cardiovascular effects by signalling through …
[HTML][HTML] Cardio-protecteffect of qiliqiangxin capsule on left ventricular remodeling, dysfunction and apoptosis in heart failure rats after chronic myocardial infarction
T Liang, Y Zhang, S Yin, T Gan, T An… - American journal of …, 2016 - ncbi.nlm.nih.gov
Background: Qiliqiangxin (QL) capsule is a traditional Chinese medicine which has been
approved for the treatment of chronic heart failure. Evidences proved that QL capsules …
approved for the treatment of chronic heart failure. Evidences proved that QL capsules …
[HTML][HTML] Qiliqiangxin attenuates phenylephrine-induced cardiac hypertrophy through downregulation of MiR-199a-5p
H Zhang, S Li, Q Zhou, Q Sun, S Shen, Y Zhou… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has long been used to
treat chronic heart failure. Previous studies demonstrated that QL could prevent cardiac …
treat chronic heart failure. Previous studies demonstrated that QL could prevent cardiac …
[HTML][HTML] Traditional Chinese medication Qiliqiangxin protects against cardiac remodeling and dysfunction in spontaneously hypertensive rats
H Wang, X Zhang, P Yu, Q Zhou, J Zhang… - … Journal of Medical …, 2017 - ncbi.nlm.nih.gov
Qiliqiangxin (QLQX), a traditional Chinese herbs medication, exerted protective effect in
chronic heart failure patients in a multicenter randomized double-blind study. QLQX has also …
chronic heart failure patients in a multicenter randomized double-blind study. QLQX has also …
Integrating evidence of the traditional chinese medicine collateral disease theory in prevention and treatment of cardiovascular continuum
I Cheang, S Liao, Q Zhu, G Ni, C Wei, Z Jia… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease has become a major public health problem. The concept of
“cardiovascular continuum” refers to the continuous process from the risk factors that lead to …
“cardiovascular continuum” refers to the continuous process from the risk factors that lead to …