Early‐life stress induces anxiety‐like behaviors and activity imbalances in the medial prefrontal cortex and amygdala in adult rats
J Ishikawa, R Nishimura… - European Journal of …, 2015 - Wiley Online Library
Early‐life stress increases the prevalence of psychiatric diseases associated with emotional
dysregulation. Emotional regulation requires the inhibitory influence of the medial prefrontal …
dysregulation. Emotional regulation requires the inhibitory influence of the medial prefrontal …
Long‐term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy
J Desloovere, P Boon, LE Larsen, C Merckx… - …, 2019 - Wiley Online Library
Objective More than one‐third of patients with temporal lobe epilepsy (TLE) continue to have
seizures despite treatment with antiepileptic drugs, and many experience severe drug …
seizures despite treatment with antiepileptic drugs, and many experience severe drug …
[HTML][HTML] The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation
Anxiety and depression are associated with increased pain responses in chronic pain
states. The extent to which anxiety drives chronic pain, or vice versa, remains an important …
states. The extent to which anxiety drives chronic pain, or vice versa, remains an important …
Trace amine-associated receptor 1 modulates motor hyperactivity, cognition, and anxiety-like behavior in an animal model of ADHD
Trace amine-associated receptor 1 (TAAR1) is a G protein-coupled receptor that has
recently been implicated in several psychiatric conditions related to monoaminergic …
recently been implicated in several psychiatric conditions related to monoaminergic …
Attention-Deficit/Hyperactivity Disorder: Focus upon Aberrant N-Methyl-d-Aspartate Receptors Systems
T Archer, D Garcia - Neurotoxin Modeling of Brain Disorders—Life-long …, 2016 - Springer
Attention-deficit/hyperactivity disorder (ADHD) pathophysiology persists in an obscure
manner with complex interactions between symptoms, staging, interventions, genes, and …
manner with complex interactions between symptoms, staging, interventions, genes, and …
Genetically determined differences in noradrenergic function: The spontaneously hypertensive rat model
TL Sterley, FM Howells, VA Russell - Brain Research, 2016 - Elsevier
While genetic predisposition is a major factor, it is not known how development of attention-
deficit/hyperactivity disorder (ADHD) is modulated by early life stress. The spontaneously …
deficit/hyperactivity disorder (ADHD) is modulated by early life stress. The spontaneously …
Anxiety correlates with somatic symptoms and sleep status at high altitudes
J Dong, J Zhang, J Qin, Q Li, W Huang, X Gao, J Yu… - Physiology & …, 2013 - Elsevier
High altitude exposure results in many physical and psychological discomforts, with anxiety
and sleep disturbances being the most common ones. This cross-sectional study was …
and sleep disturbances being the most common ones. This cross-sectional study was …
Early ethanol exposure and vinpocetine treatment alter learning‐and memory‐related proteins in the rat hippocampus and prefrontal cortex
This study investigates the effects of early exposure to ethanol on cognitive function and
neural plasticity‐related proteins in the rat brain. Sprague‐Dawley rats were administered …
neural plasticity‐related proteins in the rat brain. Sprague‐Dawley rats were administered …
Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat
TL Sterley, FM Howells, VA Russell - Brain research, 2013 - Elsevier
Recent studies have investigated the role of γ-aminobutyric acid (GABA) in the behavioural
symptoms of attention-deficit/hyperactivity disorder (ADHD), specifically in behavioural …
symptoms of attention-deficit/hyperactivity disorder (ADHD), specifically in behavioural …
The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats
T Cao, L Wang, SM Jiao, H Chen, CQ Lin… - …, 2023 - karger.com
Introduction: Progesterone receptor component 1 (PGRMC1) has been identified as a
potential target in atypical antipsychotic drug-induced metabolic disturbances as well as …
potential target in atypical antipsychotic drug-induced metabolic disturbances as well as …