[HTML][HTML] A stochastic vs deterministic perspective on the timing of cellular events
Cells are the fundamental units of life, and like all life forms, they change over time. Changes
in cell state are driven by molecular processes; of these many are initiated when molecule …
in cell state are driven by molecular processes; of these many are initiated when molecule …
Clonal dynamics of surface-driven growing tissues
RI Mukhamadiarov, M Ciarchi, F Olmeda, S Rulands - Physical Review E, 2024 - APS
The self-organization of cells into complex tissues relies on a tight coordination of cell
behavior. Identifying the cellular processes driving tissue growth is key to understanding the …
behavior. Identifying the cellular processes driving tissue growth is key to understanding the …
The timing of cellular events: a stochastic vs deterministic perspective
Changes in cell state are driven by key molecular events whose timing can often be
measured experimentally. Of particular interest is the time taken for the levels of RNA or …
measured experimentally. Of particular interest is the time taken for the levels of RNA or …
Licensing and competition of stem cells at the niche combine to regulate tissue maintenance
To maintain and regenerate adult tissues after injury, the numbers, proliferation, and
differentiation rates of tissue-resident stem cells must be precisely regulated. The regulatory …
differentiation rates of tissue-resident stem cells must be precisely regulated. The regulatory …