Recent advances on quinazoline derivatives: A potential bioactive scaffold in medicinal chemistry
This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
Advances in Palladium‐Catalyzed Decarboxylative Cycloadditions of Cyclic Carbonates, Carbamates and Lactones
Y You, Q Li, YP Zhang, JQ Zhao, ZH Wang… - …, 2022 - Wiley Online Library
Palladium‐catalyzed decarboxylative cycloadditions have emerged as highly effective
methods for constructing structurally diverse carbo‐and heterocycles because of the …
methods for constructing structurally diverse carbo‐and heterocycles because of the …
Identification of unique quinazolone thiazoles as novel structural scaffolds for potential gram-negative bacterial conquerors
J Wang, MF Ansari, CH Zhou - Journal of Medicinal Chemistry, 2021 - ACS Publications
A class of quinazolone thiazoles was identified as new structural scaffolds for potential
antibacterial conquerors to tackle dreadful resistance. Some prepared compounds exhibited …
antibacterial conquerors to tackle dreadful resistance. Some prepared compounds exhibited …
Design, synthesis, computational study and cytotoxic evaluation of some new quinazoline derivatives containing pyrimidine moiety
Quinazoline derivatives, as an important category of heterocyclic compounds, have received
much attention for the design and development of new drugs due to their various …
much attention for the design and development of new drugs due to their various …
Deep Eutectic Solvents: An Eco‐friendly Design for Drug Engineering
F Oyoun, A Toncheva, LC Henríquez… - …, 2023 - Wiley Online Library
In the spirit of circular economy and sustainable chemistry, the use of environmentally
friendly chemical products in pharmacy has become a hot topic. In recent years, organic …
friendly chemical products in pharmacy has become a hot topic. In recent years, organic …
Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases
MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
Design, synthesis, anticancer activity and docking studies of novel quinazoline-based thiazole derivatives as EGFR kinase inhibitors
The in vitro anticancer efficacy of a new series of quinazoline-based thiazole derivatives was
explored. Three cancer cell lines, MCF-7, HepG2, and A548, as well as the normal Vero cell …
explored. Three cancer cell lines, MCF-7, HepG2, and A548, as well as the normal Vero cell …
A 1, 2, 3-Triazole derivative of quinazoline exhibits antitumor activity by tethering RNF168 to SQSTM1/P62
FC Wang, B Peng, TT Ren, SP Liu, JR Du… - Journal of Medicinal …, 2022 - ACS Publications
Quinazoline and its derivatives have drawn much attention in the development of potential
antitumor agents. Here, we synthesized a series of 1, 2, 3-triazole derivatives of quinazoline …
antitumor agents. Here, we synthesized a series of 1, 2, 3-triazole derivatives of quinazoline …
Recent advances in the synthesis of 2, 3-fused quinazolinones
W Wang, PS Zou, L Pang, CX Pan, DL Mo… - Organic & Biomolecular …, 2022 - pubs.rsc.org
As one of the most important structural units in pharmaceuticals and medicinal chemistry,
quinazolinone and its derivatives exhibit a wide range of biological and pharmacological …
quinazolinone and its derivatives exhibit a wide range of biological and pharmacological …
Ultrasound-assisted transition-metal-free catalysis: a sustainable route towards the synthesis of bioactive heterocycles
B Borah, LR Chowhan - RSC advances, 2022 - pubs.rsc.org
Heterocycles of synthetic and natural origin are a well-established class of compounds
representing a broad range of organic molecules that constitute over 60% of drugs and …
representing a broad range of organic molecules that constitute over 60% of drugs and …