In most cases, multiple sclerosis (MS) begins with a relapsing-remitting course followed by
insidious disability worsening that is independent from clinically apparent relapses and is …

Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

The prevalence of multiple sclerosis (MS) and the age of affected patients are increasing
owing to increased longevity of the general population and the availability of effective …

Cognitive decline is common in multiple sclerosis and strongly affects overall quality of life.
Despite the identification of cross-sectional MRI correlates of cognitive impairment …

Objective A major challenge in multiple sclerosis (MS) research is the understanding of
silent progression and Progressive MS. Using a novel method to accurately capture upper …

Abstract Machine learning-based imaging diagnostics has recently reached or even
surpassed the level of clinical experts in several clinical domains. However, classification …

In multiple sclerosis, spontaneous remyelination is generally incomplete and heterogeneous
across patients. A high heterogeneity in remyelination may also exist across lesions within …

Objective During the natural course of multiple sclerosis (MS), the brain is exposed to aging
as well as disease effects. Brain aging can be modeled statistically; the so‐called “brain …

Multiple Sclerosis (MS) is a major cause of neurological disability, which increases
predominantly during disease progression as a result of cortical and grey matter structures …

Background: The multiple sclerosis (MS) community is highly interested in diet as a potential
protective factor against disability, but empirical evidence remains limited. Objective …