The major limitation of conventional chemotherapy drugs is their lack of specificity for cancer
cells. As a selective apoptosis-inducing agent, tumor necrosis factor (TNF)-related apoptosis …

Abstract Sine oculis homeoprotein 1 (SIX1), a prominent representative of the homeodomain
transcription factors within the SIX family, has attracted significant interest owing to its role in …

The Australian red claw crayfish Cherax quadricarinatus, an emerging species within the
freshwater aquaculture trade, is not only an ideal species for commercial production due to …

Neuropathic pain is a severe and debilitating condition caused by damage to the peripheral
nerve or central nervous system. Although several mechanisms have been identified, the …

Esophageal cancer ranks among the most prevalent malignant tumors, and esophageal
squamous cell carcinoma (ESCC) constitutes its predominant histological form. Despite its …

Background Sine oculis homeobox homolog 1 (SIX1) is a transcription factor that has
recently been identified as a crucial regulator of embryonic development and tumorigenesis …

Sine oculis homeobox homolog 1 (Six1) is a developmentally important transcription factor
that regulates cellular proliferation, apoptosis, and dissemination during embryogenesis …

Bronchial asthma is known for airway inflammation, hyperresponsiveness, and remodeling.
MicroRNAs (MiRNAs) have been involved in the development of asthma, whereas, the …

BACKGROUND Several genes, important for development, are reduced or silenced in
adulthood, and their abnormal expression has been related to the occurrence and …

Sine oculis homeobox 1 (Six1) is an important factor for embryonic development and
carcinoma malignancy. However, the localization of Six1 varies due to protein size and cell …