Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces shaping the architecture and functionality of resident …

The mammalian gut microbial community which is known as the gut microbiota comprises
trillions of bacteria, which co-evolved with the host and has a vital role in a variety of host …

The human gastrointestinal tract hosts a diverse network of microorganisms, collectively
known as the microbiota that plays an important role in health and disease. For instance, the …

Siderophores, the secondary metabolite of various microorganisms are ferric ion specific
chelators secreted under iron stressed condition. These non-ribosomal peptides have been …

Iron is an essential trace element for multicellular organisms and nearly all microorganisms.
Although iron is abundant in the environment, common forms of iron are minimally soluble …

BACKGROUND Two developments in distinct fields are converging to create interest in
discovering small molecules from the human microbiome. First, the use of genomics to guide …

The Enterobacteriaceae are a family of Gram-negative bacteria that include commensal
organisms as well as primary and opportunistic pathogens that are among the leading …

A dense resident microbial community in the gut, referred as the commensal microbiota,
coevolved with the host and is essential for many host physiological processes that include …

Iron is an essential nutrient for bacterial growth, replication, and metabolism. Humans store
iron bound to various proteins such as hemoglobin, haptoglobin, transferrin, ferritin, and …

Bacteria secrete small molecules known as siderophores to acquire iron from their
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …