Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease

V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Organelle-specific regulation of ferroptosis

X Chen, R Kang, G Kroemer, D Tang - Cell Death & Differentiation, 2021 - nature.com
Ferroptosis, a cell death modality characterized by iron-dependent lipid peroxidation, is
involved in the development of multiple pathological conditions, including ischemic tissue …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

ROS generation and antioxidant defense systems in normal and malignant cells

AV Snezhkina, AV Kudryavtseva… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

[HTML][HTML] ROS and the DNA damage response in cancer

US Srinivas, BWQ Tan, BA Vellayappan… - Redox biology, 2019 - Elsevier
Reactive oxygen species (ROS) are a group of short-lived, highly reactive, oxygen-
containing molecules that can induce DNA damage and affect the DNA damage response …

The importance of dietary antioxidants on oxidative stress, meat and milk production, and their preservative aspects in farm animals: Antioxidant action, animal health …

EN Ponnampalam, A Kiani, S Santhiravel… - Animals, 2022 - mdpi.com
Simple Summary Oxidative stress occurs within biological systems when free radicals,
classified as reactive oxygen species and reactive nitrogen species, are in excess. The …

The role of oxidative stress in physiopathology and pharmacological treatment with pro‐and antioxidant properties in chronic diseases

A García-Sánchez, AG Miranda-Díaz… - Oxidative Medicine …, 2020 - Wiley Online Library
Oxidative stress (OS) has the ability to damage different molecules and cellular structures,
altering the correct function of organs and systems. OS accumulates in the body by …

Reactive oxygen species in metabolic and inflammatory signaling

SJ Forrester, DS Kikuchi, MS Hernandes, Q Xu… - Circulation …, 2018 - Am Heart Assoc
Reactive oxygen species (ROS) are well known for their role in mediating both physiological
and pathophysiological signal transduction. Enzymes and subcellular compartments that …

[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases

CT Madreiter-Sokolowski, C Thomas, M Ristow - Redox biology, 2020 - Elsevier
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …