Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Discovering novel cancer therapies has attracted extreme interest in the last decade. In this
regard, multidrug resistance (MDR) to chemotherapies is a key challenge in cancer …

Glutathione S-transferase Mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1)
enzymes are glutathione-S-transferases with broad significance for susceptibility or …

Background: Predicting protein levels from genotypes for proteome-wide association studies
(PWAS) may provide insight into the mechanisms underlying cancer susceptibility. Methods …

Genome‐wide association studies (GWAS) have identified around 200 loci associated with
breast cancer risk. However, protein targets for these loci remain largely unknown …

Human Papillomavirus (HPV) is the most important risk factor for cervical cancer, although
not the only one. The allelic polymorphism of enzymes acting on carcinogen metabolism has …

Background The aim of this study is to investigate of the relationship between GSTM1 gene
variations and serum trace elements, plasma malondialdehyde levels in patient with …

Polymorphisms in the glutathione transferase enzymes (GSTs) genes have been associated
with susceptibility to develop breast cancer (BC), but few are known regarding its role on this …

Given the reports made about geographical differences in Colorectal Cancer (CRC)
occurrence, suggesting a link between dietary habits, genes and cancer risk, we …

The study was conducted to evaluate the frequency of polymorphisms in GSTM1 and GSTT1
genes in patients with breast cancer compared with individuals without history of cancer …