Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine
C Xue, Q Chu, Q Zheng, S Jiang, Z Bao, Y Su… - Signal transduction and …, 2022 - nature.com
Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …
Epigenetic modification refers to heritable changes in the genetic material without any …
Beyond ergosterol: Strategies for combatting antifungal resistance in Aspergillus fumigatus and Candida auris
R Cruz, WM Wuest - Tetrahedron, 2023 - Elsevier
Aspergillus fumigatus and Candida auris are historically problematic fungal pathogens
responsible for systemic infections and high mortality rates, especially in …
responsible for systemic infections and high mortality rates, especially in …
Progress on structural modification of Tetrandrine with wide range of pharmacological activities
L Mo, F Zhang, F Chen, L Xia, Y Huang, Y Mo… - Frontiers in …, 2022 - frontiersin.org
Tetrandrine (Tet), derived from the traditional Chinese herb Fangji, is a class of natural
alkaloids with the structure of bisbenzylisoquinoline, which has a wide range of …
alkaloids with the structure of bisbenzylisoquinoline, which has a wide range of …
RNA methylation‐related inhibitors: biological basis and therapeutic potential for cancer therapy
H Chen, H Liu, C Zhang, N Xiao, Y Li… - Clinical and …, 2024 - Wiley Online Library
RNA methylation is widespread in nature. Abnormal expression of proteins associated with
RNA methylation is strongly associated with a number of human diseases including cancer …
RNA methylation is strongly associated with a number of human diseases including cancer …
Pyrrolidine dithiocarbamate enhances the cytotoxic effect of arsenic trioxide on acute promyelocytic leukemia cells
S Yu, Z Ge, W Chen, J Han - Combinatorial Chemistry & High …, 2023 - ingentaconnect.com
Background: More than 95% patients with acute promyelocytic leukemia (APL) carry the
PML-RARα fusion oncoprotein. Arsenic trioxide (ATO) is an efficacious therapeutic agent for …
PML-RARα fusion oncoprotein. Arsenic trioxide (ATO) is an efficacious therapeutic agent for …
Design, synthesis, and biological evaluation of N14-amino acid-substituted tetrandrine derivatives as potential antitumor agents against human colorectal cancer
YC Wang, RH Zhang, SC Hu, H Zhang, D Yang… - Molecules, 2022 - mdpi.com
As a typical dibenzylisoquinoline alkaloid, tetrandrine (TET) is clinically used for the
treatment of silicosis, inflammatory pulmonary, and cardiovascular diseases in China …
treatment of silicosis, inflammatory pulmonary, and cardiovascular diseases in China …