Advanced computational methodologies used in the discovery of new natural anticancer compounds
Natural chemical compounds have been widely investigated for their programmed necrosis
causing characteristics. One of the conventional methods for screening such compounds is …
causing characteristics. One of the conventional methods for screening such compounds is …
Beneficial effects of UV radiation other than via vitamin D production
A Juzeniene, J Moan - Dermato-endocrinology, 2012 - Taylor & Francis
Most of the positive effects of solar radiation are mediated via ultraviolet-B (UVB) induced
production of vitamin D in skin. However, several other pathways may exist for the action of …
production of vitamin D in skin. However, several other pathways may exist for the action of …
Vitamin D deficiency increases mortality risk in the UK biobank: a nonlinear mendelian randomization study
JP Sutherland, A Zhou, E Hyppönen - Annals of internal medicine, 2022 - acpjournals.org
Background: Low vitamin D status is associated with increased mortality, but randomized
trials on severely deficient participants are lacking. Objective: To assess genetic evidence …
trials on severely deficient participants are lacking. Objective: To assess genetic evidence …
Chimeric HDAC inhibitors: Comprehensive review on the HDAC‐based strategies developed to combat cancer
HM Hesham, DS Lasheen… - Medicinal Research …, 2018 - Wiley Online Library
Recently, molecular hybridization paradigm became an interesting and smart way to defeat
the multifaceted cancer disease by a single molecular entity that acts via several …
the multifaceted cancer disease by a single molecular entity that acts via several …
Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors
AKA Bass, MS El-Zoghbi, ESM Nageeb… - European journal of …, 2021 - Elsevier
Despite the encouraging clinical progress of chemotherapeutic agents in cancer treatment,
innovation and development of new effective anticancer candidates still represents a …
innovation and development of new effective anticancer candidates still represents a …
Vitamin D and regulation of vascular cell function
N Jamali, CM Sorenson… - American Journal of …, 2018 - journals.physiology.org
Vitamin D deficiency is linked to pathogenesis of many diseases including cardiovascular,
cancer, and various eye diseases. In recent years, important roles for vitamin D in regulation …
cancer, and various eye diseases. In recent years, important roles for vitamin D in regulation …
The vitamin D–folate hypothesis as an evolutionary model for skin pigmentation: an update and integration of current ideas
Vitamin D is unique in being generated in our skin following ultraviolet radiation (UVR)
exposure. Ongoing research into vitamin D must therefore always consider the influence of …
exposure. Ongoing research into vitamin D must therefore always consider the influence of …
A review on regulation of cell cycle by extracellular matrix
The extracellular matrix (ECM) is a network of structural proteins, glycoproteins and
proteoglycans that assists independent cells in aggregating and forming highly organized …
proteoglycans that assists independent cells in aggregating and forming highly organized …
Potential molecular mechanisms of the anti-cancer activity of vitamin D
D Skrajnowska, B Bobrowska-Korczak - Anticancer research, 2019 - ar.iiarjournals.org
Vitamin D, or more precisely its active metabolite calcitriol (1, 25-(OH) 2D3), plays a
fundamental role in bone metabolism and differentiation as well as in intestinal absorption of …
fundamental role in bone metabolism and differentiation as well as in intestinal absorption of …
Evidence-based complementary treatment of pancreatic cancer: A review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins …
S Bigelsen - Cancer Management and Research, 2018 - Taylor & Francis
Despite new and exciting research and renewed optimism about future therapy, current
statistics of survival from pancreatic cancer remains dismal. Patients seeking alternative or …
statistics of survival from pancreatic cancer remains dismal. Patients seeking alternative or …