[HTML][HTML] Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Relationship between biofilm formation and antimicrobial resistance in gram-negative bacteria

V Cepas, Y López, E Muñoz, D Rolo… - Microbial Drug …, 2019 - liebertpub.com
Gram-negative microorganisms are a significant cause of infection in both community and
nosocomial settings. The increase, emergence, and spread of antimicrobial resistance …

Biofilm-specific antibiotic tolerance and resistance

I Olsen - European Journal of Clinical Microbiology & Infectious …, 2015 - Springer
Biofilms are heterogeneous structures composed of bacterial cells surrounded by a matrix
and attached to solid surfaces. The bacteria here are 100 to 1,000 times more tolerant to …

[HTML][HTML] Clinical Impact of Antibiotics for the Treatment of Pseudomonas aeruginosa Biofilm Infections

E Olivares, S Badel-Berchoux, C Provot… - Frontiers in …, 2020 - frontiersin.org
Bacterial biofilms are highly recalcitrant to antibiotic therapies due to multiple tolerance
mechanisms. The involvement of Pseudomonas aeruginosa in a wide range of biofilm …

[HTML][HTML] Microbial biofilms and chronic wounds

A Omar, JB Wright, G Schultz, R Burrell, P Nadworny - Microorganisms, 2017 - mdpi.com
Background is provided on biofilms, including their formation, tolerance mechanisms,
structure, and morphology within the context of chronic wounds. The features of biofilms in …

Biofilm infections, their resilience to therapy and innovative treatment strategies

U Römling, C Balsalobre - Journal of internal medicine, 2012 - Wiley Online Library
Biofilm formation of microorganisms causes persistent tissue and foreign body infections
resistant to treatment with antimicrobial agents. Up to 80% of human bacterial infections are …

[HTML][HTML] Relationship between Antibiotic Resistance, Biofilm Formation, and Biofilm-Specific Resistance in Acinetobacter baumannii

L Qi, H Li, C Zhang, B Liang, J Li, L Wang… - Frontiers in …, 2016 - frontiersin.org
In this study, we aimed to examine the relationships between antibiotic resistance, biofilm
formation, and biofilm-specific resistance in clinical isolates of Acinetobacter baumannii. The …

SOS, the formidable strategy of bacteria against aggressions

Z Baharoglu, D Mazel - FEMS microbiology reviews, 2014 - academic.oup.com
The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …

Biofilm-specific antibiotic resistance

TF Mah - Future microbiology, 2012 - Future Medicine
Bacterial biofilms are the basis of many persistent diseases. The persistence of these
infections is primarily attributed to the increased antibiotic resistance exhibited by the cells …