Coordinating Proliferation, Polarity, and Cell Fate in the Drosophila Female Germline

TD Hinnant, JA Merkle, ET Ables - Frontiers in cell and …, 2020 - frontiersin.org
Gametes are highly specialized cell types produced by a complex differentiation process.
Production of viable oocytes requires a series of precise and coordinated molecular events …

Ecdysone signalling and ovarian development in insects: from stem cells to ovarian follicle formation

X Belles, MD Piulachs - Biochimica et Biophysica Acta (BBA)-Gene …, 2015 - Elsevier
Although a great deal of information is available concerning the role of ecdysone in insect
oogenesis, research has tended to focus on vitellogenesis and choriogenesis. As such, the …

Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary

W Niu, AC Spradling - … of the National Academy of Sciences, 2020 - National Acad Sciences
We sequenced more than 52,500 single cells from embryonic day 11.5 (E11. 5)
postembryonic day 5 (P5) gonads and performed lineage tracing to analyze primordial …

Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homolog Eip75B in Drosophila

L Zipper, D Jassmann, S Burgmer, B Görlich, T Reiff - elife, 2020 - elifesciences.org
Developmental studies revealed fundamental principles on how organ size and function is
achieved, but less is known about organ adaptation to new physiological demands. In fruit …

Midgut-derived neuropeptide F controls germline stem cell proliferation in a mating-dependent manner

T Ameku, Y Yoshinari, MJ Texada, S Kondo… - PLoS …, 2018 - journals.plos.org
Stem cell maintenance is established by neighboring niche cells that promote stem cell self-
renewal. However, it is poorly understood how stem cell activity is regulated by systemic …

The neuropeptide allatostatin C from clock-associated DN1p neurons generates the circadian rhythm for oogenesis

C Zhang, I Daubnerova, YH Jang… - Proceedings of the …, 2021 - National Acad Sciences
The link between the biological clock and reproduction is evident in most metazoans. The
fruit fly Drosophila melanogaster, a key model organism in the field of chronobiology …

The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster

CM Hunter, W Huang, TFC Mackay, ND Singh - PLoS genetics, 2016 - journals.plos.org
Meiotic recombination ensures proper chromosome segregation in many sexually
reproducing organisms. Despite this crucial function, rates of recombination are highly …

Recent progress in understanding the role of ecdysteroids in adult insects: Germline development and circadian clock in the fruit fly Drosophila melanogaster

O Uryu, T Ameku, R Niwa - Zoological letters, 2015 - Springer
Steroid hormones are one of the major bioactive molecules responsible for the coordinated
regulation of biological processes in multicellular organisms. In insects, the principal steroid …

Role of endocrine system in the regulation of female insect reproduction

MZ Khalid, S Ahmad, PM Ngegba, G Zhong - Biology, 2021 - mdpi.com
Simple Summary The abundance of insects indicates that they are one of the most
adaptable forms of life on earth. Genetic, physiological, and biochemical plasticity and the …

Local and Physiological Control of Germline Stem Cell Lineages in Drosophila melanogaster

D Drummond-Barbosa - Genetics, 2019 - academic.oup.com
The long-term survival of any multicellular species depends on the success of its germline in
producing high-quality gametes and maximizing survival of the offspring. Studies in …