The elaboration of the vasculature during embryonic development involves restructuring of
the early vessels into a more complex vascular network. Of particular importance to this …

Kaposi's sarcoma (KS) is caused by Kaposi's sarcoma–associated herpesvirus (KSHV) and
consists of proliferating spindle cells, which are related to lymphatic endothelial cells (LEC) …

Although mouse models of inflammatory skin diseases such as psoriasis and atopic
dermatitis fail to completely phenocopy disease in humans, they provide invaluable tools to …

Animal models are valuable and necessary for the purpose of better understanding the
mechanisms underlying disease processes and for the development and evaluation of novel …

This review focuses on association between the selectivity of Bcr-Abl kinase inhibitors and
the spectrum of their adverse effects during treatment of patients with chronic myeloid …

Pericytes are a previously understudied, but crucial cell type of the vessel wall. In the brain,
pericytes are part of the neurovascular unit and are involved in the control and regulation of …

Abstract Human Tie1 and Tie2 receptor tyrosine kinases (RTKs) are signaling molecules
with important pathophysiological functions in many diseases, including different cancers …

This review focuses on association between the selectivity of Bcr-Abl kinase inhibitors and
the spectrum of their adverse effects during treatment of patients with chronic myeloid …

Conditional systems have proven to be efficient and powerful to delineate several aspects of
cardiac pathophysiology and diseases. The possibility of addressing a particular time point …