Many studies report that expression of Flk1 is crucial for early establishment of endothelial
and hematopoietic lineages and perhaps for their common progenitor. 5, 11, 12 Flk1 …

Blood vessels form extensive networks that nurture all tissues. Paracrine signaling between
the platelet-derived growth factor (Pdgf-b)-secreting endothelial cells (ECs) of nascent …

The vasculature has a crucial function in normal physiology, enabling the transport of
oxygen and nutrients to cells throughout the body. In turn, endothelial cells, which form the …

Hereditary hemorrhagic telangiectasia (HHT) and inflammatory bowel disease (IBD) are
associated with pathological angiogenesis. Vascular endothelial growth factor, VEGF, is a …

L'angiogenèse, caractérisée par la formation de nouveaux vaisseaux sanguins à partir de
vaisseaux préexistants, est un processus accompagné par l'inflammation, impliquant la …

The cardiovascular system develops through two distinct processes in embryogenesis:
vasculogenesis, whereby the primary plexus in the heart is formed along with embryonic …

Angiopoietins are ligands for the endothelial cell-specific Tie-2 receptors. Angiopoietin-1
(Ang-1) activates Tie-2 receptors in the vasculature and promotes endothelial cell survival …

Background There is ongoing debate regarding the initiation of psoriatic plaque as primarily
arising from an anomaly in epidermal keratinocytes (KCs) or from abnormalities in …

The aim of this study was to characterize the cellular mechanisms leading to the beneficial
effect of anti-oxidative gene therapy and pro-angiogenic stem cell therapy in acute …

A functioning vasculature is critical for the supply of nutrients to all organ systems as well as
for a host of physiologic and pathologic processes. Vascular development and maintenance …