Neurodegenerative diseases comprise a wide spectrum of pathologies characterized by
progressive loss of neuronal functions and structures. Despite having different genetic …

The process of aging refers to physiological changes that occur to an organism as time
progresses and involves changes to DNA, proteins, metabolism, cells, and organs. Like the …

Epigenetic regulation plays a crucial role in the pathogenesis of autoimmune diseases such
as inflammatory arthritis. DNA hypomethylating agents, such as decitabine (DAC), have …

Alzheimer's disease (AD) is a prevalent type of dementia in elderly populations with a
significant genetic component. The accumulating evidence suggests that AD involves a …

Infections caused by acute respiratory viruses induce a systemic innate immune response,
which can be measured by the increased levels of expression of inflammatory genes in …

Abstract Circular RNAs (CircRNAs) are non-coding RNAs (ncRNAs) characterized by a
stable circular structure that regulates gene expression at both transcriptional and post …

Epigenetic changes are important considerations for degenerative diseases. DNA
methylation regulates crucial genes by epigenetic mechanism, impacting cell function and …

Decidual macrophages are the second-largest immune cell group at the maternal-foetal
interface. They participate in apoptotic cell removal, and protect the foetus from …

Phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase (PI3K), and protein
kinase B (Akt) signaling pathways contribute to the development of several cancers …

Despite efforts to ban asbestos mining and manufacturing, mesothelioma deaths in the
United States have remained stable around 2500 cases annually. This trend is not unique to …