Curcumin as a potential treatment for COVID-19

BAC Rattis, SG Ramos, MRN Celes - Frontiers in pharmacology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is an infectious disease that rapidly spread
throughout the world leading to high mortality rates. Despite the knowledge of previous …

Liver regeneration after hepatectomy and partial liver transplantation

S Yagi, M Hirata, Y Miyachi, S Uemoto - International Journal of …, 2020 - mdpi.com
The liver is a unique organ with an abundant regenerative capacity. Therefore, partial
hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver …

Molecular basis of skin photoaging and therapeutic interventions by plant-derived natural product ingredients: A comprehensive review

MA Tanveer, H Rashid, SA Tasduq - Heliyon, 2023 - cell.com
Skin areas exposed to ultraviolet radiation (UV) from sunlight are more prone to photoaging
than unexposed areas evidenced by several signs which include skin dryness, irregular …

The targets of curcumin

H Zhou, CS Beevers, S Huang - Current drug targets, 2011 - ingentaconnect.com
Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature

FM Millimouno, J Dong, L Yang, J Li, X Li - Cancer prevention research, 2014 - AACR
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …

Modulation of NF-κB signalling by microbial pathogens

MM Rahman, G McFadden - Nature Reviews Microbiology, 2011 - nature.com
The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …

Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation

Y Tian, H Li, T Qiu, J Dai, Y Zhang, J Chen, H Cai - Aging cell, 2019 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is an aging‐associated disease with poor prognosis.
Currently, there are no effective drugs for preventing the disease process. The mechanisms …

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

C Freudlsperger, Y Bian, S Contag Wise, J Burnett… - Oncogene, 2013 - nature.com
Transforming growth factor-beta (TGF-β) has a dual role in epithelial malignancies, including
head and neck squamous cell carcinoma (HNSCC). Attenuation of canonical TGF-β …

Redox regulation by protein S-glutathionylation: from molecular mechanisms to implications in health and disease

A Musaogullari, YC Chai - International journal of molecular sciences, 2020 - mdpi.com
S-glutathionylation, the post-translational modification forming mixed disulfides between
protein reactive thiols and glutathione, regulates redox-based signaling events in the cell …

NF-κB signalling as a pharmacological target in COVID-19: potential roles for IKKβ inhibitors

M Kandasamy - Naunyn-Schmiedeberg's archives of pharmacology, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has been characterized by lymphopenia as
well as a proinflammatory cytokine storm, which are responsible for the poor prognosis and …