Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Biomedical applications of microfluidic devices: a review

G Gharib, İ Bütün, Z Muganlı, G Kozalak, İ Namlı… - Biosensors, 2022 - mdpi.com
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …

Microfluidic tissue engineering and bio‐actuation

M Filippi, T Buchner, O Yasa, S Weirich… - Advanced …, 2022 - Wiley Online Library
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Recent progress in translational engineered in vitro models of the central nervous system

P Nikolakopoulou, R Rauti, D Voulgaris, I Shlomy… - Brain, 2020 - academic.oup.com
The complexity of the human brain poses a substantial challenge for the development of
models of the CNS. Current animal models lack many essential human characteristics (in …

Mechanisms of radiation-induced endothelium damage: Emerging models and technologies

H Wijerathne, JC Langston, Q Yang, S Sun… - Radiotherapy and …, 2021 - Elsevier
Radiation-induced endothelial/vascular injury is a major complicating factor in radiotherapy
and a leading cause of morbidity and mortality in nuclear or radiological catastrophes …

Modeling the human body on microfluidic chips

S Jalili-Firoozinezhad, CC Miranda, JMS Cabral - Trends in biotechnology, 2021 - cell.com
Animals often fail to faithfully mimic human diseases and drug toxicities, and most in vitro
models are not complex enough to recapitulate human body function and pathophysiology …

A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it

A Varone, JK Nguyen, L Leng, R Barrile, J Sliz… - Biomaterials, 2021 - Elsevier
Successful translation of in vivo experimental data to human patients is an unmet need and
a bottleneck in the development of effective therapeutics. Organ-on-Chip technology aims to …

Traditional vs. Microfluidic synthesis of zno nanoparticles

ML Popa, MD Preda, IA Neacșu… - International Journal of …, 2023 - mdpi.com
Microfluidics provides a precise synthesis of micro-/nanostructures for various applications,
including bioengineering and medicine. In this review article, traditional and microfluidic …

Microfluidics for rapid detection of live pathogens

C Spatola Rossi, F Coulon, S Ma… - Advanced Functional …, 2023 - Wiley Online Library
Rapid, sensitive, and selective detection of live pathogens remains a key priority for quality
control and risk assessment. While conventional methods often require complicated …

Recent advances in fed-batch microscale bioreactor design

S Teworte, K Malcı, LE Walls, M Halim… - Biotechnology …, 2022 - Elsevier
Advanced fed-batch microbioreactors mitigate scale up risks and more closely mimic
industrial cultivation practices. Recently, high throughput microscale feeding strategies have …