Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

S Prasad, A Chandra, M Cavo, E Parasido… - …, 2020 - iopscience.iop.org
The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two
of the most characterized properties of the TME are acidosis and hypoxia, both of which are …

Quantitative analysis of yeast MAPK signaling networks and crosstalk using a microfluidic device

B Lee, SG Jeong, SH Jin, R Mishra, M Peter, CS Lee… - Lab on a Chip, 2020 - pubs.rsc.org
Eukaryotic cells developed complex mitogen-activated protein kinase (MAPK) signaling
networks to sense their intra-and extracellular environment and respond to various stress …

A Photoreceptor‐Based Hydrogel with Red Light‐Responsive Reversible Sol‐Gel Transition as Transient Cellular Matrix

M Hörner, J Becker, R Bohnert, M Baños… - Advanced Materials …, 2023 - Wiley Online Library
Hydrogels with adjustable mechanical properties have been engineered as matrices for
mammalian cells and allow the dynamic, mechano‐responsive manipulation of cell fate and …

Projection micro-stereolithography to manufacture a biocompatible micro-optofluidic device for cell concentration monitoring

L Saitta, E Cutuli, G Celano, C Tosto, D Sanalitro… - Polymers, 2023 - mdpi.com
In this work, a 3D printed biocompatible micro-optofluidic (MoF) device for two-phase flow
monitoring is presented. Both an air–water bi-phase flow and a two-phase mixture …

Towards personalized antibody cancer therapy: development of a microfluidic cell culture device for antibody selection

PGM Condelipes, PM Fontes, A Godinho-Santos… - Lab on a Chip, 2022 - pubs.rsc.org
Antibody therapy has been one of the most successful therapies for a wide range of
diseases, including cancer. One way of expediting antibody therapy development is through …

Direct Production of a Hyperpolarized Metabolite on a Microfluidic Chip

SJ Barker, L Dagys, W Hale, B Ripka, J Eills… - Analytical …, 2022 - ACS Publications
Microfluidic systems hold great potential for the study of live microscopic cultures of cells,
tissue samples, and small organisms. Integration of hyperpolarization would enable …

Microfluidic systems as a novel approach for microalgal bioprocess

B Karacaoğlu, B İnan, DB Özçimen - Biochemical Engineering Journal, 2023 - Elsevier
Challenges such as controlling parameters for microalgal bioprocess optimization,
increased need for inoculum and chemicals with the increasing number of experiments, long …

Recent trends on the development of systems for cancer diagnosis and treatment by microfluidic technology

ACQ Silva, C Vilela, HA Santos, AJD Silvestre… - Applied Materials …, 2020 - Elsevier
Cancer is the second leading cause of non-accidental death in the world, accounting for
roughly 9.6 million deaths in 2018. In the latter years, research in this domain has grown …

Exploring the potential of drug response assays for precision medicine in ovarian cancer

T Singh, AS Neal, NA Moatamed… - International Journal of …, 2020 - mdpi.com
One of the major challenges in the treatment of cancer are differential responses of patients
to existing standard of care anti-cancer drugs. These differential responses may, in part, be …

Fabrication and characterisation of a silicon-borosilicate glass microfluidic device for synchrotron-based hard X-ray spectroscopy studies

PM Raj, L Barbe, M Andersson, MDA Moreira… - RSC …, 2021 - pubs.rsc.org
Some of the most fundamental chemical building blocks of life on Earth are the metal
elements. X-ray absorption spectroscopy (XAS) is an element-specific technique that can …