Cardiac fibrosis constitutes irreversible necrosis of the heart muscle as a consequence of
different acute (myocardial infarction) or chronic (diabetes, hypertension,…) diseases but …

Heart failure (HF) is characterized by a progressive decline in cardiac function and
represents one of the largest health burdens worldwide. Clinically, 2 major types of HF are …

Cardiovascular magnetic resonance (CMR) imaging has become an essential technique for
the assessment of cardiac function and morphology, and is now routinely used to monitor …

Background Diffuse interstitial myocardial fibrosis is a key common pathological
manifestation in hypertensive heart disease (HHD) progressing to heart failure (HF) …

Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left
ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural …

Background Left atrial (LA) fibrosis is a marker of atrial cardiomyopathy and has been
reported to be associated with both atrial fibrillation and ischemic stroke. Elucidating this …

BACKGROUND: Compared with patients with hypertension only, those with hypertension
and diabetes (HTN/DM) have worse prognosis. We aimed to characterize morphological …

Class A, rhodopsin‐like, G‐protein‐coupled receptors (GPCRs) are by far the largest class
of GPCRs and are integral membrane proteins used by various cells to convert extracellular …

Background Heart failure is caused by acute or chronic cardiovascular diseases with limited
treatments and unclear pathogenesis. Therefore, it is urgent to explore new therapeutic …

Hypertensive crisis can present with cardiac troponin elevation and unobstructed coronary
arteries. We used cardiac magnetic resonance (CMR) imaging to characterize the …