Riding the tiger–physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix
MD Brand - Critical Reviews in Biochemistry and Molecular Biology, 2020 - Taylor & Francis
Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …
wide range of physiological responses and pathologies. Concentrations of superoxide and …
Manganese superoxide dismutase dysfunction and the pathogenesis of kidney disease
M Kitada, J Xu, Y Ogura, I Monno, D Koya - Frontiers in physiology, 2020 - frontiersin.org
The mitochondria are a major source of reactive oxygen species (ROS). Superoxide anion
(O2•–) is produced by the process of oxidative phosphorylation associated with glucose …
(O2•–) is produced by the process of oxidative phosphorylation associated with glucose …
Novel insights into redox system and the mechanism of redox regulation
X Wang, C Hai - Molecular Biology Reports, 2016 - Springer
In view of the critical role of redox system in numerous physiological and pathophysiological
processes, it is important to clearly understand the family members and regulatory …
processes, it is important to clearly understand the family members and regulatory …
[HTML][HTML] Role of superoxide dismutase 2 gene Ala16Val polymorphism and total antioxidant capacity in diabetes and its complications
Diabetes Mellitus (DM) is a chronic heterogeneous disorder and oxidative stress is a key
participant in the development and progression of it and its complications. Anti-oxidant …
participant in the development and progression of it and its complications. Anti-oxidant …
Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC‐1α Signaling in db/db Mice
S Hou, T Zhang, Y Li, F Guo… - Journal of diabetes …, 2017 - Wiley Online Library
Diabetic nephropathy (DN) is a major cause of end‐stage renal disease (ESRD).
Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production …
Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production …
[HTML][HTML] Concentration/activity of superoxide dismutase isozymes and the pro-/antioxidative status, in context of type 2 diabetes and selected single nucleotide …
Ł Lewandowski, I Urbanowicz, M Kepinska… - Biomedicine & …, 2021 - Elsevier
The alterations in concentration/activity of superoxide dismutase isozymes in the context of
type 2 diabetes or obesity are well-described. Moreover, many hereditary factors, including …
type 2 diabetes or obesity are well-described. Moreover, many hereditary factors, including …
Pro198Leu polymorphism in the glutathione peroxidase 1 gene contributes to diabetic peripheral neuropathy in type 2 diabetes patients
M Buraczynska, K Buraczynska, M Dragan… - Neuromolecular …, 2017 - Springer
Abstract Glutathione peroxidase 1 (Gpx1) is an endogenous antioxidant enzyme. The T
allele of the Pro198Leu polymorphism in the Gpx1 (rs1050450, 198C> T) gene is associated …
allele of the Pro198Leu polymorphism in the Gpx1 (rs1050450, 198C> T) gene is associated …
[HTML][HTML] Role of long non-coding RNA (LncRNA) LINC-PINT downregulation in cardiomyopathy and retinopathy progression among patients with type 2 diabetes
T Zha, F Su, X Liu, C Yang, L Liu - Medical science monitor …, 2019 - ncbi.nlm.nih.gov
Role of Long Non-Coding RNA (LncRNA) LINC-PINT Downregulation in Cardiomyopathy and
Retinopathy Progression Among Patients with Type 2 Diabetes - PMC Back to Top Skip to main …
Retinopathy Progression Among Patients with Type 2 Diabetes - PMC Back to Top Skip to main …
Manganese superoxide dismutase, glutathione peroxidase and catalase gene polymorphisms and clinical outcomes in acute kidney injury
V Kidir, E Uz, A Yigit, A Altuntas, B Yigit, S Inal, E Uz… - Renal …, 2016 - Taylor & Francis
Introduction The aim of this study was to evaluate the potential association of single gene
polymorphisms of manganese superoxide dismutase (MnSOD), glutathione peroxidase 1 …
polymorphisms of manganese superoxide dismutase (MnSOD), glutathione peroxidase 1 …
Therapeutic implications of superoxide dismutase and its importance in kinase drug discovery
In recent years, several scientific investigations have reported the therapeutic implications of
superoxide dismutase (SOD) against oxidative stress and-induced pathology in clinical and …
superoxide dismutase (SOD) against oxidative stress and-induced pathology in clinical and …