Reduced functional ability and exercise tolerance in patients with heart failure (HF) are
associated with poor quality of life and a worse prognosis. The 6-minute walking test …

Exercise intolerance is the cardinal symptom of heart failure (HF) and is of crucial relevance,
because it is associated with a poor quality of life and increased mortality. While impaired …

Aim The aim of this study was to evaluate the benefits and safety of long-term iv iron therapy
in iron-deficient patients with heart failure (HF). Methods and results CONFIRM-HF was a …

Background: Patients with chronic heart failure (HF) secondary to left ventricular systolic
dysfunction (LVSD) are frequently deficient in vitamin D. Low vitamin D levels are associated …

Objectives: This study sought to assess the impact of continuous flow left ventricular assist
devices (LVADs) on functional capacity and heart failure-related quality of life. Background …

The assessment of functional capacity reflects the ability to perform activities of daily living
that require sustained aerobic metabolism. The integrated efforts and health of the …

Rationale: Outcomes other than spirometry are required to assess nonbronchodilator
therapies for chronic obstructive pulmonary disease. Estimates of the minimal clinically …

OBJECTIVES: To estimate the relationship between 1‐year improvement in measures of
health and physical function and 8‐year survival. DESIGN: Prospective cohort study …

The classes of recommendations and levels of evidence in these guidelines were
determined and described according to the “Guidelines for the treatment of acute and …

Rationale: CD34+ transplantation in dilated cardiomyopathy was associated with short-term
improvement in left ventricular ejection fraction and exercise tolerance. Objective: We …