Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

Immunomodulatory and allergenic properties of antimicrobial peptides

SV Guryanova, TV Ovchinnikova - International journal of molecular …, 2022 - mdpi.com
With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

Host defense peptides: Dual antimicrobial and immunomodulatory action

M Drayton, JP Deisinger, KC Ludwig… - International Journal of …, 2021 - mdpi.com
The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …

Translational aspect in peptide drug discovery and development: An emerging therapeutic candidate

U Anand, A Bandyopadhyay, NK Jha… - Biofactors, 2023 - Wiley Online Library
In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …

Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens

JE Nielsen, MA Alford, DBY Yung… - ACS infectious …, 2022 - ACS Publications
Antimicrobial peptides (AMPs) are promising pharmaceutical candidates for the prevention
and treatment of infections caused by multidrug-resistant ESKAPE pathogens, which are …

Antibiofilm properties of cathelicidin LL-37: an in-depth review

H Memariani, M Memariani - World Journal of Microbiology and …, 2023 - Springer
Notwithstanding ceaseless endeavors toward developing effective antibiofilm
chemotherapeutics, biofilm-associated infections continue to be one of the most perplexing …

Vesicoureteral reflux and innate immune system: Physiology, physiopathology, and clinical aspects

MC Colceriu, PL Aldea, AL Răchișan… - Journal of Clinical …, 2023 - mdpi.com
Vesicoureteral reflux represents one of the most concerning topics in pediatric nephrology
due to its frequency, clinical expression with the potential to evolve into chronic kidney …

Antifungal properties of cathelicidin LL-37: current knowledge and future research directions

M Memariani, H Memariani - World Journal of Microbiology and …, 2024 - Springer
The threat of fungal diseases is substantially underestimated worldwide, but they have
serious consequences for humans, animals, and plants. Given the limited number of existing …

Antimicrobial and pro-angiogenic properties of soluble and nanoparticle-immobilized LL37 peptides

M Comune, A Rai, P Palma, C TondaTuro… - Biomaterials …, 2021 - pubs.rsc.org
Antimicrobial peptides (AMPs), such as LL37 peptides, may be immobilized on the surface
of medical devices to render them with antimicrobial and angiogenic properties. However …

In Vivo Acute Toxicity and Therapeutic Potential of a Synthetic Peptide, DP1 in a Staphylococcus aureus Infected Murine Wound Excision Model

P Barman, C Sharma, S Joshi, S Sharma… - Probiotics and …, 2023 - Springer
Bacterial infections at the surgical sites are one of the most prevalent skin infections that
impair the healing mechanism. They account for about 20% of all types of infections and …