In the vasculature, reactive oxidant species, including reactive oxygen, nitrogen, or
halogenating species, and thiyl, tyrosyl, or protein radicals may oxidatively modify lipids and …

The idea that atherosclerosis is an inflammatory disease is no longer controversial. Instead,
much of the current research is now focused on understanding what drives this inflammation …

Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …

A preponderance of evidence obtained from genetically modified mice and human
population studies reveals the association of apolipoprotein E (apoE) deficiency and …

Objective—Chemokines and their receptors are crucially involved in the development of
atherosclerotic lesions by directing monocyte and T cell recruitment. The CC-chemokine …

Abstract Statins, the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, are effective
serum cholesterol-lowering agents in clinical practice, and they may also have anti …

OBJECTIVE: The olive oil-rich Mediterranean diet protects against cardiovascular disease,
which involves inflammatory processes. This study investigated the effects of phenolic …

Research during the last two decades established atheromatous lesions as active sites of
inflammation and immune responses, contrasting to the traditional view of atherosclerosis as …

Rationale: CD4 T cells are involved in the pathogenesis of atherosclerosis, but
atherosclerosis-specific CD4 T cells have not been described. Moreover, the chemokine (s) …

Interleukins are considered to be key players in the chronic vascular inflammatory response
that is typical of atherosclerosis. Thus, the expression of proinflammatory interleukins and …