[HTML][HTML] The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …

Cannabidiol goes nuclear: The role of PPARγ

S Khosropoor, MS Alavi, L Etemad, A Roohbakhsh - Phytomedicine, 2023 - Elsevier
Background Cannabidiol (CBD) is one of the main phytocannabinoids found in Cannabis
sativa. In contrast to Δ9-tetrahydrocannabinol, it has a low affinity for cannabinoid receptors …

[HTML][HTML] A single dose of cannabidiol (CBD) positively influences measures of stress in dogs during separation and car travel

ABG Hunt, HE Flint, DW Logan, T King - Frontiers in Veterinary …, 2023 - frontiersin.org
Many dogs experience stress when separated from their caregivers, as well as when
travelling in vehicles. Pet owners employ various approaches to managing these issues …

[HTML][HTML] The role of cannabidiol in aging

B Ni, Y Liu, M Dai, J Zhao, Y Liang, X Yang… - Biomedicine & …, 2023 - Elsevier
Aging is usually considered a key risk factor associated with multiple diseases, such as
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …

[HTML][HTML] Opportunities, challenges and pitfalls of using cannabidiol as an adjuvant drug in COVID-19

B Malinowska, M Baranowska-Kuczko… - International journal of …, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may lead to
coronavirus disease 2019 (COVID-19) which, in turn, may be associated with multiple organ …

[HTML][HTML] Resolvin D2 and its receptor GPR18 in cardiovascular and metabolic diseases: A promising biomarker and therapeutic target

M Zhao, Z Zheng, Z Yin, J Zhang, J Qin, J Wan… - Pharmacological …, 2023 - Elsevier
Accumulating evidence suggests that inflammation plays an important role in the
pathophysiology of the initiation and progression of cardiovascular and metabolic diseases …

[HTML][HTML] Cannabidiol attenuates pulmonary arterial hypertension by improving vascular smooth muscle cells mitochondrial function

X Lu, J Zhang, H Liu, W Ma, L Yu, X Tan, S Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Pulmonary arterial hypertension (PAH) is a chronic disease associated with
enhanced proliferation of pulmonary artery smooth muscle cells (PASMCs) and …

[HTML][HTML] CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial

M Kumric, G Dujic, J Vrdoljak, K Svagusa… - Biomedicine & …, 2023 - Elsevier
Data concerning the effects of cannabidiol (CBD) on blood pressure (BP) is controversial.
HYPER-H21–4 was a randomized, placebo-controlled, crossover trial which sought to …

[HTML][HTML] Molecular and biochemical mechanism of cannabidiol in the management of the inflammatory and oxidative processes associated with endometriosis

T Genovese, M Cordaro, R Siracusa… - International journal of …, 2022 - mdpi.com
Endometriosis is usually associated with inflammation and chronic pelvic pain. This paper
focuses the attention on the anti-inflammatory, anti-oxidant and analgesic effects of …

[HTML][HTML] Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway in monocrotaline-induced pulmonary hypertension in …

A Krzyżewska, M Baranowska-Kuczko… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Cannabidiol (CBD) is a non-intoxicating compound of Cannabis with anti-fibrotic properties.
Pulmonary hypertension (PH) is a disease that can lead to right ventricular (RV) failure and …