Glycoprotein synthesis: an update

DP Gamblin, EM Scanlan, BG Davis - Chemical Reviews, 2009 - ACS Publications
1.1 Aims This review updates our original review on the synthesis of glycoproteins.(1) Its
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …

Enzymes in the synthesis of glycoconjugates

RM Schmaltz, SR Hanson, CH Wong - Chemical reviews, 2011 - ACS Publications
Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

[图书][B] Hydrolases in organic synthesis: regio-and stereoselective biotransformations

UT Bornscheuer, RJ Kazlauskas - 2006 - books.google.com
From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …

Engineering of glycosidases and glycosyltransferases

SM Hancock, MD Vaughan, SG Withers - Current opinion in chemical …, 2006 - Elsevier
In recent years, substantial advances have been made in the engineering of glycosidases
and glycosyltransferases for the synthesis and degradation of glycan structures. Key …

Glycosyltransferase-catalyzed synthesis of bioactive oligosaccharides

CAGM Weijers, MCR Franssen, GM Visser - Biotechnology advances, 2008 - Elsevier
Mammalian cell surfaces are all covered with bioactive oligosaccharides which play an
important role in molecular recognition events such as immune recognition, cell–cell …

[HTML][HTML] Progress and challenges in the synthesis of sequence controlled polysaccharides

G Fittolani, T Tyrikos-Ergas, D Vargová… - Beilstein Journal of …, 2021 - beilstein-journals.org
The sequence, length and substitution of a polysaccharide influence its physical and
biological properties. Thus, sequence controlled polysaccharides are important targets to …

Recent advances in organocatalytic glycosylations

R Williams, MC Galan - European Journal of Organic Chemistry, 2017 - Wiley Online Library
Carbohydrates play a pivotal role in biological systems and present an opportunity to
develop potent carbohydrate‐derived therapeutics and diagnostic tools for the treatment and …

Enzymatic glycosyl transfer: mechanisms and applications

T Desmet, W Soetaert - Biocatalysis and Biotransformation, 2011 - Taylor & Francis
Glycosylated compounds have numerous applications in the food, pharmaceutical and
personal care industries. Their synthesis is, however, far from trivial. Because chemical …

Glycosynthases in biocatalysis

B Cobucci‐Ponzano, A Strazzulli… - Advanced Synthesis …, 2011 - Wiley Online Library
Glycosynthases, engineered glycoside hydrolases that are able to synthesize glycans in
quantitative yields without hydrolyzing them, are among the most interesting tools for the …

[PDF][PDF] A glycosynthase catalyst for the synthesis of flavonoid glycosides

M Yang, GJ Davies, BG Davis - Angewandte Chemie International …, 2007 - users.ox.ac.uk
Glycosylation of lipophilic small molecules is one of the predominant strategies by which the
bioactivity of these compounds is modulated in living organisms.[1–4] Indeed, even simple …