In this study, the genetic diversification of the catalytic nucleophile of the prokaryotic β-
galactosidase from Bacillus circulans (BgaC) was investigated in terms of a novel synthetic …

Glycosidic compounds are chemical structures that consist of sugars molecules or that have
a sugar attached to another molecule. They are now already used in various industries and …

1 INTRODUCTION 12. In the recent decades, the application of enzymes in synthetic
organic chemistry became attractive alternatives to classical synthetic routes due to …

The synthesis of glycosidic bonds is of high commercial value, because the produced
compounds can be used for a wide range of applications. Oligosaccharides, for example …

The current drive for applications of biomassderived compounds, for energy and advanced
materials, has led to a resurgence of interest in the manipulation of plant polymers. The …

Xyloglucan is widely used in bulk quantities in the food, textile and paper making industries.
With an increasing interest in technically more advanced applications of xyloglucan, such as …

Galactooligosaccharides are produced by the transglycosylation activity of β-galactosidases
(β-gal, EC 3.2. 1.23) when utilising lactose as a substrate. They have emerged as important …

Background Carbohydrate-active enzymes (cazymes) are enzymatic activities involved in
the hydrolysis, synthesis, recognition, and binding of carbohydrates, thereby contributing to …

The overexpresssion of gangliosides in melanoma and several other tumors of
neuroectodermal origin makes these molecules attractive targets for the development of …