Adjuvant treatment strategy after curative resection for hepatocellular carcinoma

W Zhang, B Zhang, X Chen - Frontiers of medicine, 2021 - Springer
Hepatic resection represents the first-line treatment for patients with resectable
hepatocellular carcinoma (HCC). However, the 5-year recurrence rates of HCC after surgery …

Natural products targeting tumour angiogenesis

X Lu, LJ Friedrich, T Efferth - British journal of pharmacology, 2023 - Wiley Online Library
Tumour angiogenesis is the formation of new blood vessels to support the growth of a
tumour. This process is critical for tumour progression and metastasis, making it an attractive …

Effects of adjuvant traditional Chinese medicine therapy on long-term survival in patients with hepatocellular carcinoma

XL Liu, MG Li, X Wang, Z Dang, L Yu, XB Wang… - Phytomedicine, 2019 - Elsevier
Background Many patients with hepatocellular carcinoma (HCC) in Asian countries seek
adjuvant therapy with traditional Chinese medicine (TCM). This study aims to explore the …

[HTML][HTML] Hypoxia‑inducible factors in hepatocellular carcinoma

Y Guo, Z Xiao, L Yang, Y Gao, Q Zhu… - Oncology …, 2020 - spandidos-publications.com
Maintenance of an appropriate oxygen concentration is essential for the function of the liver.
However, in many pathological conditions, and particularly in the tumor microenvironment …

[HTML][HTML] Chinese herbal medicine for primary liver cancer therapy: perspectives and challenges

K Li, K Xiao, S Zhu, Y Wang, W Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Primary liver cancer (PLC) is one of the most common solid malignancies. However, PLC
drug development has been slow, and first-line treatments are still needed; thus, studies …

[HTML][HTML] Natural products: a promising therapeutics for targeting tumor angiogenesis

R Li, X Song, Y Guo, P Song, D Duan… - Frontiers in oncology, 2021 - frontiersin.org
Tumor-associated angiogenesis is a key target for anti-cancer therapy. The imbalance
between pro-angiogenic and anti-angiogenic signals elicited by tumor cells or tumor …

[HTML][HTML] miR-451 acts as a suppressor of angiogenesis in hepatocellular carcinoma by targeting the IL-6R-STAT3 pathway

X Liu, A Zhang, J Xiang, Y Lv… - Oncology …, 2016 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is a highly vascularized tumor and the third ranking
contributor of tumor-associated death. Our previous study corroborated the inhibitory roles of …

Protective effects of polysaccharides on hepatic injury: A review

Y Yuan, L Che, C Qi, Z Meng - International journal of biological …, 2019 - Elsevier
Chronic hepatic injury caused by hepatitis B and C virus (HBV and HCV) infection, high fat
diet and alcohol intake has increased to be the critical promoter of hepatocellular carcinoma …

[HTML][HTML] An immune-stimulating proteoglycan from the medicinal mushroom Huaier up-regulates NF-κB and MAPK signaling via Toll-like receptor 4

A Yang, H Fan, Y Zhao, X Chen, Z Zhu, X Zha… - Journal of Biological …, 2019 - ASBMB
Trametes robiniophila Murr.(Huaier) is a mushroom with a long history of use as a medicinal
ingredient in China and exhibits good clinical efficacy in cancer management. However, the …

RETRACTED: Huaier extract suppresses non‐small cell lung cancer progression through activating NLRP3‐dependent pyroptosis

J Xie, B Zhuan, H Wang, Y Wang, X Wang… - The Anatomical …, 2021 - Wiley Online Library
Recent studies have reported the anticancer activity of huaier extract in various human
malignancies. However, little is known about the effect of huaier extract in non‐small cell …